(Q38366424)

2 September 2017

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title

p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis (English)

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2 September 2017

Gene Wiki Review Series

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Sara Cabodi

6

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author name string

Maria del Pilar Camacho Leal

1

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2 September 2017

Marianna Sciortino

2

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2 September 2017

Giusy Tornillo

3

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2 September 2017

Shana Colombo

4

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2 September 2017

Paola Defilippi

5

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2 September 2017

language of work or name

English

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publication date

27 February 2015

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2 September 2017

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2 September 2017

562

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2 September 2017

1

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2 September 2017

1-7

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YopH dephosphorylates Cas and Fyn-binding protein in macrophages

2 September 2017

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12 December 2020

CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells

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12 December 2020

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

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12 December 2020

Requirement of the p130CAS-Crk Coupling for Metastasis Suppressor KAI1/CD82-mediated Inhibition of Cell Migration

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12 December 2020

Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins

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12 December 2020

The prognostic value of BCAR1 in patients with primary breast cancer.

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12 December 2020

Activation of a signaling cascade by cytoskeleton stretch

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12 December 2020

Uncoupling Crk signal transduction by Pseudomonas exoenzyme T.

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12 December 2020

The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions

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12 December 2020

p130Cas: a versatile scaffold in signaling networks

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12 December 2020

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

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12 December 2020

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

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12 December 2020

BCAR1 expression in prostate cancer: association with 16q23 LOH status, tumor progression and EGFR/KAI1 staining.

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12 December 2020

p130CAS is required for netrin signaling and commissural axon guidance

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12 December 2020

Crk-associated substrate (Cas) signaling protein functions with integrins to specify axon guidance during development

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12 December 2020

Global analysis of patterns of gene expression during Drosophila embryogenesis

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12 December 2020

The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways

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12 December 2020

Relation among p130Cas, E-cadherin and beta-catenin expression, clinicopathologic significance and prognosis in human hepatocellular carcinoma

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12 December 2020

p130 Crk-associated substrate (CAS) in vascular smooth muscle.

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12 December 2020

CAS proteins in normal and pathological cell growth control

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12 December 2020

p130Cas is an essential transducer element in ErbB2 transformation

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12 December 2020

p130Cas, Crk-associated substrate plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration

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12 December 2020

Dcas supports cell polarization and cell-cell adhesion complexes in development

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12 December 2020

Expression of Estrogen Related Proteins in Hormone Refractory Prostate Cancer: Association With Tumor Progression

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12 December 2020

p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1

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12 December 2020

Integrin signalling adaptors: not only figurants in the cancer story

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12 December 2020

Systematizing and cloning of genes involved in the cerebellar cortex circuit development.

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12 December 2020

Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells

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12 December 2020

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas

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12 December 2020

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

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12 December 2020

NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation

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12 December 2020

Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness

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12 December 2020

Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death

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12 December 2020

EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation

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12 December 2020

CrkI and p130(Cas) complex regulates the migration and invasion of prostate cancer cells

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12 December 2020

BCAR1 expression improves prediction of biochemical reccurence after radical prostatectomy

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12 December 2020

p130Cas-dependent actin remodelling regulates myogenic differentiation.

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12 December 2020

CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model

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12 December 2020

A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents

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12 December 2020

p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells

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12 December 2020

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

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12 December 2020

p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.

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12 December 2020

p130Cas: a key signalling node in health and disease

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12 December 2020

Skeletal muscle adaptation in response to mechanical stress in p130cas-/- mice

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12 December 2020

p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.

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12 December 2020

p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity

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12 December 2020

Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells.

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12 December 2020

CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics.

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12 December 2020

The emerin-binding transcription factor Lmo7 is regulated by association with p130Cas at focal adhesions

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12 December 2020

The 31-kDa caspase-generated cleavage product of p130Cas antagonizes the action of MyoD during myogenesis

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12 December 2020

Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling

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12 December 2020

Oligodendroglial p130Cas is a target of Fyn kinase involved in process formation, cell migration and survival

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12 December 2020

Integrin αv in the mechanical response of osteoblast lineage cells

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12 December 2020

A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.

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12 December 2020

P130cas is required for TGF-β1-mediated epithelial-mesenchymal transition in lung cancer

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12 December 2020

CAS proteins in health and disease: an update

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12 December 2020

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

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12 December 2020

p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells

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12 December 2020

LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix

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12 December 2020

Cas proteins: dodgy scaffolding in breast cancer

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12 December 2020

Tyrosine phosphorylation of p130Cas is involved in actin organization in osteoclasts.

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12 December 2020

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

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12 December 2020

10.1016/J.GENE.2015.02.027

Identifiers

DOI

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2 September 2017

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