(Q38367012)

2 September 2017

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title

Role of sGC-dependent NO signalling and myocardial infarction risk (English)

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2 September 2017

myocardial infarction

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4

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2 September 2017

5

Heribert Schunkert

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2 September 2017

Jana Wobst

1

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2 September 2017

Thorsten Kessler

series ordinal

2

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2 September 2017

Tan An Dang

series ordinal

3

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2 September 2017

4 March 2015

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Journal of Molecular Medicine

2 September 2017

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2 September 2017

93

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2 September 2017

4

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2 September 2017

383-394

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https://scigraph.springernature.com/pub.10.1007/s00109-015-1265-3

2 September 2017

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cites work

Mortality from ischaemic heart disease by country, region, and age: statistics from World Health Organisation and United Nations

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https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Large-scale association analysis identifies new risk loci for coronary artery disease

21 January 2018

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Dysfunctional nitric oxide signalling increases risk of myocardial infarction

21 January 2018

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Nitric oxide: a cytotoxic activated macrophage effector molecule

21 January 2018

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

21 January 2018

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide synthase: non-canonical expression patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Structure-function aspects in the nitric oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

The majority of nitric oxide synthase in pig heart is vascular and not neural

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Regulation and functional consequences of endothelial nitric oxide formation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitrite reduction and cardiovascular protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Expression of soluble guanylyl cyclase. Catalytic activity requires two enzyme subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide-induced conformational changes in soluble guanylate cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Signal transduction mechanisms involving nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide-sensitive guanylyl cyclase is the only nitric oxide receptor mediating platelet inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Molecular cloning of a novel variant of the rat soluble guanylate cyclase beta2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Tissue distribution of the human soluble guanylate cyclases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Functional properties of a naturally occurring isoform of soluble guanylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Molecular cloning and expression of a new α&#x2010;subunit of soluble guanylyl cyclase Interchangeability of the α&#x2010;subunits of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Functional role of the soluble guanylyl cyclase alpha(1) subunit in vascular smooth muscle relaxation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Phosphodiesterase regulation of nitric oxide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Phosphodiesterases and cyclic GMP regulation in heart muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Phosphodiesterase type 5: expanding roles in cardiovascular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Allosteric-site and catalytic-site ligand effects on PDE5 functions are associated with distinct changes in physical form of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Modulation of platelet aggregation by an L-arginine-nitric oxide pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide: an endogenous modulator of leukocyte adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

S-nitrosylation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Soluble guanylate cyclase alpha(1) and beta(1) gene transfer increases NO responsiveness and reduces neointima formation after balloon injury in rats via antiproliferative and antimigratory effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

An integrated map of genetic variation from 1,092 human genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Genetic predisposition to higher blood pressure increases coronary artery disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

CCTeta, a novel soluble guanylyl cyclase-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Therapeutic Potential of the Nitrite-Generated NO Pathway in Vascular Dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Blood pressure loci identified with a gene-centric array

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Target sequencing, cell experiments, and a population study establish endothelial nitric oxide synthase (eNOS) gene as hypertension susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

T-786C polymorphism in the endothelial nitric oxide synthase gene is associated with increased risk of coronary artery disease in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Endothelial nitric oxide synthase gene polymorphisms -786T > C and 894G > T in coronary artery bypass graft surgery patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Association between the - 786T>C 1polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) and risk of coronary artery disease: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Endothelial nitric oxide synthase gene G894T polymorphism and myocardial infarction: a meta-analysis of 34 studies involving 21,068 subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Association of endothelial nitric oxide synthase gene polymorphisms with classical risk factors in development of premature coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Lack of association between Glu298Asp polymorphism and coronary artery disease in North Indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

The endothelial nitric oxide synthase gene is associated with coronary artery disease: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1α knock-in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

More answers to the still unresolved question of nitrate tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

NO-independent regulatory site on soluble guanylate cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Randomized clinical trials--removing obstacles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

An open-label, long-term evaluation of the safety, efficacy and tolerability of avanafil in male patients with mild to severe erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Long-term treatment with sildenafil citrate in pulmonary arterial hypertension: the SUPER-2 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Efficacy and safety of sildenafil citrate in men with erectile dysfunction and stable coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Effect of sildenafil on cardiac performance in patients with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-015-1265-3

Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation

21 January 2018

1 reference

12 December 2020

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.

1 reference

12 December 2020

Localization of the heme binding region in soluble guanylate cyclase

1 reference

12 December 2020

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1 reference

12 December 2020

Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction

1 reference

12 December 2020

A large blood pressure-raising effect of nitric oxide synthase inhibition in humans

1 reference

12 December 2020

Enzyme-independent formation of nitric oxide in biological tissues

1 reference

12 December 2020

Long-term nitrate treatment increases cardiac events in patients with healed myocardial infarction. Secondary Prevention Group

1 reference

12 December 2020

Therapy of endocrine disease. Effects of chronic use of phosphodiesterase inhibitors on endothelial markers in type 2 diabetes mellitus: a meta-analysis

1 reference

12 December 2020

The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile

1 reference

12 December 2020

Characterization of a purified bovine lung cGMP-binding cGMP phosphodiesterase

1 reference

12 December 2020

Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population

1 reference

12 December 2020

Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses

1 reference

12 December 2020

Effects of cyclic GMP on smooth muscle relaxation.

1 reference

12 December 2020

Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations.

1 reference

12 December 2020

Vardenafil for treatment of men with erectile dysfunction: efficacy and safety in a randomized, double-blind, placebo-controlled trial.

1 reference

12 December 2020

Association of a polymorphism of the ecNOS gene with myocardial infarction in a subgroup of Turkish MI patients

1 reference

12 December 2020

T(-786)--> C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with myocardial infarction, especially without coronary organic stenosis

1 reference

12 December 2020

Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells

1 reference

12 December 2020

A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK

1 reference

12 December 2020

Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies

1 reference

12 December 2020

Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis

1 reference

12 December 2020

Sildenafil in primary pulmonary hypertension--is there a subset of patients who respond favourably?

1 reference

12 December 2020

Riociguat for pulmonary hypertension

1 reference

12 December 2020

The role of oxidized phospholipids in atherosclerosis

1 reference

12 December 2020

The relationship between endothelial nitric oxide synthase 4a/4b gene polymorphism and premature coronary artery disease.

1 reference

12 December 2020

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G

1 reference

12 December 2020

Endothelial nitric oxide synthase gene polymorphisms and the risk of acute myocardial infarction in a South Indian population

1 reference

12 December 2020

Soluble guanylate cyclase from rat lung exists as a heterodimer

1 reference

12 December 2020

Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis

1 reference

12 December 2020

Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein

1 reference

12 December 2020

Cyclic GMP synthesis and function

1 reference

12 December 2020

Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.

1 reference

12 December 2020

Endothelial nitric oxide gene polymorphisms, nitric oxide production and coronary artery disease risk in a South Indian population

1 reference

12 December 2020

Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans

1 reference

12 December 2020

10.1007/S00109-015-1265-3

Identifiers

DOI

1 reference

Dimensions Publication ID

2 September 2017

0 references

1 reference