(Q38369597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

review article

1 reference

title

Delivery of therapeutic oligonucleotides with cell penetrating peptides (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1

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2 March 2020

Sébastien Deshayes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Matthew J. Wood

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Michael J Gait

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Liz O'Donovan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Caroline Godfrey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Corinne A Betts

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Bernard Lebleu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

4 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

Advanced Drug Delivery Reviews

2 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747758%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

52-67

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The antisense transcriptomes of human cells

2 March 2020

cites work

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12 December 2020

Myotonic dystrophy type 2: molecular, diagnostic and clinical spectrum

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12 December 2020

Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo.

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12 December 2020

Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development

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12 December 2020

Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery

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12 December 2020

Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

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12 December 2020

Effective exon skipping and restoration of dystrophin expression by peptide nucleic acid antisense oligonucleotides in mdx mice

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12 December 2020

Molecular parameters of siRNA--cell penetrating peptide nanocomplexes for efficient cellular delivery.

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12 December 2020

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.

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12 December 2020

Oligonucleotide-poly(L-lysine)-heparin complexes: potent sequence-specific inhibitors of HIV-1 infection

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12 December 2020

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

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12 December 2020

Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice.

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12 December 2020

Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes

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12 December 2020

The endothelial glycocalyx: composition, functions, and visualization

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12 December 2020

Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.

1 reference

12 December 2020

Single acute-dose and repeat-doses toxicity of anti-HIV-1 PNA TAR-penetratin conjugate after intraperitoneal administration to mice

1 reference

12 December 2020

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

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12 December 2020

Development of a general methodology for labelling peptide-morpholino oligonucleotide conjugates using alkyne-azide click chemistry

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12 December 2020

Self-assembling peptide-based nanoparticles for siRNA delivery in primary cell lines.

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12 December 2020

Use of cell-penetrating-peptides in oligonucleotide splice switching therapy.

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12 December 2020

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

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12 December 2020

Comparison of cellular uptake using 22 CPPs in 4 different cell lines.

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12 December 2020

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

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12 December 2020

X chromosome-linked muscular dystrophy (mdx) in the mouse

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12 December 2020

A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells

1 reference

12 December 2020

Direct translocation as major cellular uptake for CADY self-assembling peptide-based nanoparticles

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12 December 2020

Local dystrophin restoration with antisense oligonucleotide PRO051

1 reference

12 December 2020

Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles.

1 reference

12 December 2020

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

1 reference

12 December 2020

Peptide-based nanoparticle for ex vivo and in vivo drug delivery

1 reference

12 December 2020

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

1 reference

12 December 2020

Membrane perturbation effects of peptides derived from the N-termini of unprocessed prion proteins

1 reference

12 December 2020

Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo.

1 reference

12 December 2020

Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue

1 reference

12 December 2020

Cell entry of cell penetrating peptides: tales of tails wagging dogs

1 reference

12 December 2020

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

1 reference

12 December 2020

Polyarginine enters cells more efficiently than other polycationic homopolymers

1 reference

12 December 2020

Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.

1 reference

12 December 2020

Melittin derived peptides for nanoparticle based siRNA transfection

1 reference

12 December 2020

Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice

1 reference

12 December 2020

Antisense peptide-phosphorodiamidate morpholino oligomer conjugate: dose-response in mice infected with Escherichia coli.

1 reference

12 December 2020

Therapeutic potential of splice-switching oligonucleotides

1 reference

12 December 2020

Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis.

1 reference

12 December 2020

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

1 reference

12 December 2020

Arginine-rich peptides: potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms

1 reference

12 December 2020

RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system

1 reference

12 December 2020

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models

1 reference

12 December 2020

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

1 reference

12 December 2020

Silencing of microRNA families by seed-targeting tiny LNAs

1 reference

12 December 2020

Antisense technology: a selective tool for gene expression regulation and gene targeting

1 reference

12 December 2020

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

1 reference

12 December 2020

Biomimetic amplification of nanoparticle homing to tumors

1 reference

12 December 2020

Cellular trafficking determines the exon skipping activity of Pip6a-PMO in mdx skeletal and cardiac muscle cells.

1 reference

12 December 2020

Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia

1 reference

12 December 2020

Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse

1 reference

12 December 2020

Serum stability and physicochemical characterization of a novel amphipathic peptide C6M1 for siRNA delivery

1 reference

12 December 2020

Cell-penetrating-peptide-based delivery of oligonucleotides: an overview

1 reference

12 December 2020

Structural polymorphism of non-covalent peptide-based delivery systems: highway to cellular uptake.

1 reference

12 December 2020

Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers

1 reference

12 December 2020

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

12 December 2020

Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways.

1 reference

12 December 2020

Multifunctional polymeric micelles for delivery of drugs and siRNA.

1 reference

12 December 2020

Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

1 reference

12 December 2020

Induction of splice correction by cell-penetrating peptide nucleic acids

1 reference

12 December 2020

Targeted gene modification of hematopoietic progenitor cells in mice following systemic administration of a PNA-peptide conjugate

1 reference

12 December 2020

Everything you always wanted to know about CADY-mediated siRNA delivery* (* but afraid to ask).

1 reference

12 December 2020

Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain

1 reference

12 December 2020

Cationic amphipathic histidine-rich peptides for gene delivery.

1 reference

12 December 2020

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid

1 reference

12 December 2020

Calcium ions effectively enhance the effect of antisense peptide nucleic acids conjugated to cationic tat and oligoarginine peptides

1 reference

12 December 2020

Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery.

1 reference

12 December 2020

Anti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides

1 reference

12 December 2020

In vivo antitumor effect of methotrexate conjugated to a monoclonal IgM antibody specific for stage-specific embryonic antigen-1, on MH-15 mouse teratocarcinoma

1 reference

12 December 2020

Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.

1 reference

12 December 2020

Antisense inhibition of gene expression and growth in gram-negative bacteria by cell-penetrating peptide conjugates of peptide nucleic acids targeted to rpoD gene.

1 reference

12 December 2020

Fomivirsen: clinical pharmacology and potential drug interactions

1 reference

12 December 2020

Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs

1 reference

12 December 2020

Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates

1 reference

12 December 2020

Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA.

1 reference

12 December 2020

The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.

1 reference

12 December 2020

Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer

1 reference

12 December 2020

Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma

1 reference

12 December 2020

Metal free, "click and click-click" conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase

1 reference

12 December 2020

A peptide carrier for the delivery of biologically active proteins into mammalian cells.

1 reference

12 December 2020

Physicochemical characterization of siRNA-peptide complexes

1 reference

12 December 2020

Cell penetrating peptides: overview and applications to the delivery of oligonucleotides

1 reference

12 December 2020

Heparan sulfate-independent cell binding and infection with furin-precleaved papillomavirus capsids

1 reference

12 December 2020

A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.

1 reference

12 December 2020

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

1 reference

12 December 2020

Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology

1 reference

12 December 2020

Systemic administration of PRO051 in Duchenne's muscular dystrophy

1 reference

12 December 2020

A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

1 reference

12 December 2020

An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection

1 reference

12 December 2020

Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer

1 reference

12 December 2020

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

1 reference

12 December 2020

Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice

1 reference

12 December 2020

Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

1 reference

12 December 2020

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions.

1 reference

12 December 2020

Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.

1 reference

12 December 2020

Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy

1 reference

12 December 2020

Eteplirsen for the treatment of Duchenne muscular dystrophy

1 reference

12 December 2020

A novel potent strategy for gene delivery using a single peptide vector as a carrier

1 reference

12 December 2020

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

1 reference

12 December 2020

Cell-penetrating peptides as versatile vehicles for oligonucleotide delivery

1 reference

12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus

1 reference

12 December 2020

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

1 reference

12 December 2020

Strategies in the design of nanoparticles for therapeutic applications

1 reference

12 December 2020

Online Mendelian Inheritance in Man (OMIM).

1 reference

12 December 2020

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

1 reference

12 December 2020

Regulation by small RNAs in bacteria: expanding frontiers

1 reference

12 December 2020

Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy

1 reference

12 December 2020

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor

1 reference

12 December 2020

Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

1 reference

12 December 2020

The agony of choice: how to find a suitable CPP for cargo delivery

1 reference

12 December 2020

A non-covalent peptide-based carrier for in vivo delivery of DNA mimics

1 reference

12 December 2020

Targeting RNA to treat neuromuscular disease

1 reference

12 December 2020

Peptide conjugation of 2'-O-methyl phosphorothioate antisense oligonucleotides enhances cardiac uptake and exon skipping in mdx mice

1 reference

12 December 2020

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

1 reference

12 December 2020

Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement

1 reference

12 December 2020

Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc

1 reference

12 December 2020

The third helix of the Antennapedia homeodomain translocates through biological membranes.

1 reference

12 December 2020

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

1 reference

12 December 2020

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

1 reference

12 December 2020

Homing peptides as targeted delivery vehicles.

1 reference

12 December 2020

A new amphipathic, amino-acid-pairing (AAP) peptide as siRNA delivery carrier: physicochemical characterization and in vitro uptake.

1 reference

12 December 2020

Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.

1 reference

12 December 2020

Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.

1 reference

12 December 2020

Glycosaminoglycans in the cellular uptake of drug delivery vectors - bystanders or active players?

1 reference

12 December 2020

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

1 reference

12 December 2020

Disulfide conjugation of peptides to oligonucleotides and their analogs

1 reference

12 December 2020

Update on the management of Duchenne muscular dystrophy

1 reference

12 December 2020

Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy

1 reference

12 December 2020

Assessing the delivery efficacy and internalization route of cell-penetrating peptides

1 reference

12 December 2020

Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells

1 reference

12 December 2020

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

1 reference

12 December 2020

Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide

1 reference

12 December 2020

Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development.

1 reference

12 December 2020

Translocation and endocytosis for cell-penetrating peptide internalization

1 reference

12 December 2020

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

1 reference

12 December 2020

Pathway for polyarginine entry into mammalian cells

1 reference

12 December 2020

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

1 reference

12 December 2020

On the mechanism of non-endosomial peptide-mediated cellular delivery of nucleic acids.

1 reference

12 December 2020

Cell-penetrating peptides: tools for intracellular delivery of therapeutics.

1 reference

12 December 2020

Cell penetration by transportan.

1 reference

12 December 2020

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

1 reference

12 December 2020

Pharmacokinetics and safety of single doses of drisapersen in non-ambulant subjects with Duchenne muscular dystrophy: results of a double-blind randomized clinical trial

1 reference

12 December 2020

HIV-1 Tat protein can transactivate a heterologous TATAA element independent of viral promoter sequences and the trans-activation response element

1 reference

12 December 2020

Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis.

1 reference

12 December 2020

LNA-mediated microRNA silencing in non-human primates

1 reference

12 December 2020

Interactions of amphipathic CPPs with model membranes

1 reference

12 December 2020

Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis.

1 reference

12 December 2020

Insights into the cellular trafficking of splice redirecting oligonucleotides complexed with chemically modified cell-penetrating peptides

1 reference

12 December 2020

Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy.

1 reference

12 December 2020

Mechanisms of nanoparticle-mediated siRNA transfection by melittin-derived peptides

1 reference

12 December 2020

Peptide-mediated cell delivery: application in protein target validation

1 reference

12 December 2020

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

1 reference

12 December 2020

Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle.

1 reference

12 December 2020

Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells

1 reference

12 December 2020

A versatile method for the preparation of conjugates of peptides with DNA/PNA/analog by employing chemo-selective click reaction in water

1 reference

12 December 2020

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

1 reference

12 December 2020

Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate

1 reference

12 December 2020

Peptide nucleic acid antisense oligomer as a therapeutic strategy against bacterial infection: proof of principle using mouse intraperitoneal infection

1 reference

12 December 2020

Systemic vascular safety of ranibizumab for age-related macular degeneration: systematic review and meta-analysis of randomized trials

1 reference

12 December 2020

A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells

1 reference

12 December 2020

Advanced morpholino oligomers: a novel approach to antiviral therapy

1 reference

12 December 2020

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

1 reference

12 December 2020

Bactericidal antisense effects of peptide-PNA conjugates.

1 reference

12 December 2020

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment.

1 reference

12 December 2020

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

1 reference

12 December 2020

Elucidation of muscle-binding peptides by phage display screening

1 reference

12 December 2020

Molecular mechanisms of muscular dystrophies: old and new players

1 reference

12 December 2020

Live-cell analysis of cell penetration ability and toxicity of oligo-arginines

1 reference

12 December 2020

The molecular basis of muscular dystrophy in the mdx mouse: a point mutation

1 reference

12 December 2020

Antennapedia homeobox as a signal for the cellular internalization and nuclear addressing of a small exogenous peptide.

1 reference

12 December 2020

Insight into the cellular uptake mechanism of a secondary amphipathic cell-penetrating peptide for siRNA delivery.

1 reference

12 December 2020

Chances and pitfalls of cell penetrating peptides for cellular drug delivery

1 reference

12 December 2020

Octaarginine-modified multifunctional envelope-type nano device for siRNA.

1 reference

12 December 2020

The respiratory management of patients with duchenne muscular dystrophy: a DMD care considerations working group specialty article

1 reference

12 December 2020

Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides

1 reference

12 December 2020

Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.

1 reference

12 December 2020