(Q38391372)

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Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease

scientific article published on 21 April 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

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Europe PubMed Central

Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

Lyndsay L Leach

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Dennis O Clegg

2

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Europe PubMed Central

PubMed publication ID

2 September 2017

publication date

21 April 2015

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Europe PubMed Central

PubMed publication ID

2 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

33

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Europe PubMed Central

PubMed publication ID

2 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

2363-2373

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Embryonic stem cell lines derived from human blastocysts

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Prevalence of age-related macular degeneration in the United States

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Prevalence of age-related macular degeneration in the US population

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

The retinal pigment epithelium in visual function

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Age-related macular degeneration--emerging pathogenetic and therapeutic concepts

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Embryonic stem cell trials for macular degeneration: a preliminary report

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Developing cellular therapies for retinal degenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Pluripotent human stem cells for the treatment of retinal disease

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Three-dimensional early retinal progenitor 3D tissue constructs derived from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Stepwise differentiation of pluripotent stem cells into retinal cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Retinal pigment epithelium development, plasticity, and tissue homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Human embryonic stem cell applications for retinal degenerations

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Human pluripotent stem cell-derived retinal pigmented epithelium in retinal treatment: from bench to bedside

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Using human induced pluripotent stem cells to treat retinal disease

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Generation of retinal cells from mouse and human induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Directed differentiation of telencephalic precursors from embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Engineering efficient retinal pigment epithelium differentiation from human pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

A new efficient protocol for directed differentiation of retinal pigmented epithelial cells from normal and retinal disease induced pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Self-formation of optic cups and storable stratified neural retina from human ESCs.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Efficient generation of retinal progenitor cells from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Canonical Wnt/β-catenin signalling is essential for optic cup formation

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Modeling early retinal development with human embryonic and induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Functional analysis of serially expanded human iPS cell-derived RPE cultures

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Considerations for tissue-engineered and regenerative medicine product development prior to clinical trials in the United States

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Nonxenogeneic growth and retinal differentiation of human induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Potency assay development for cellular therapy products: an ISCT review of the requirements and experiences in the industry

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https://api.crossref.org/works/10.1002%2FSTEM.2010

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MSC-based product characterization for clinical trials: an FDA perspective

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https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

RP2 phenotype and pathogenetic correlations in X-linked retinitis pigmentosa

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Safety and efficacy of gene transfer for Leber's congenital amaurosis

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Patient-Specific Induced Pluripotent Stem Cell-Derived RPE Cells: Understanding the Pathogenesis of Retinopathy in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Gyrate atrophy with hyperornithinaemia: different types of responsiveness to vitamin B6.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Immunology of age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.2010

21 January 2018

Identifiers

10.1002/STEM.2010

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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