(Q38405069)

2 September 2017

An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology (English)

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2 September 2017

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Nathalie Streichenberger

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Nathalie Streichenberger

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Herbert Budka

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Herbert Budka

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Gabor G. Kovacs

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Gabor G Kovacs

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author name string

Uta Wagner

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2 September 2017

Benoit Dumont

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2 September 2017

Maria Pikkarainen

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2 September 2017

Awad A Osman

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2 September 2017

Irene Leisser

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2 September 2017

Jérémy Verchère

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2 September 2017

Thierry Baron

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2 September 2017

Irina Alafuzoff

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2 September 2017

Armand Perret-Liaudet

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2 September 2017

Ingolf Lachmann

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2 September 2017

28 February 2012

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2 September 2017

Acta Neuropathologica

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2 September 2017

124

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2 September 2017

1

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2 September 2017

37-50

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https://scigraph.springernature.com/pub.10.1007/s00401-012-0964-x

2 September 2017

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cites work

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Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease.

21 January 2018

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The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease

21 January 2018

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A broken alpha -helix in folded alpha -Synuclein

21 January 2018

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Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

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Comparative study of commercially available anti-alpha-synuclein antibodies.

21 January 2018

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Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

21 January 2018

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Biochemical staging of synucleinopathy and amyloid deposition in dementia with Lewy bodies.

21 January 2018

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Widespread alterations of alpha-synuclein in multiple system atrophy

21 January 2018

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Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases.

21 January 2018

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Alpha-synuclein and neurodegenerative diseases

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Consensus prediction of amyloidogenic determinants in amyloid fibril-forming proteins.

21 January 2018

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Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

21 January 2018

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 January 2018

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Human postmortem brain tissue and 2-mm tissue microarrays.

21 January 2018

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A semi-empirical method for prediction of antigenic determinants on protein antigens

21 January 2018

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Protein coding of neurodegenerative dementias: the neuropathological basis of biomarker diagnostics

21 January 2018

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Novel alpha-synuclein-immunoreactive proteins in brain samples from the Contursi kindred, Parkinson's, and Alzheimer's disease.

21 January 2018

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Human brain tissue microarrays as a platform to investigate diseases of the nervous system.

21 January 2018

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Alpha-synuclein and the pathogenesis of Parkinson's disease

21 January 2018

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Biochemical characterization of the core structure of alpha-synuclein filaments

21 January 2018

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α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

21 January 2018

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Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus

21 January 2018

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Use of the phage display technique for detection of epitopes recognized by polyclonal rabbit gliadin antibodies

21 January 2018

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Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

21 January 2018

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The effect of prolonged fixation time on immunohistochemical staining of common neurodegenerative disease markers.

21 January 2018

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Molecular determinants of the aggregation behavior of alpha- and beta-synuclein

21 January 2018

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Accumulation of phosphorylated alpha-synuclein in aging human brain.

21 January 2018

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Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

21 January 2018

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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

21 January 2018

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The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

21 January 2018

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Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression.

21 January 2018

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Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation

21 January 2018

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

21 January 2018

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Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid

21 January 2018

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The fold of alpha-synuclein fibrils

21 January 2018

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Characterization of antibodies that selectively detect alpha-synuclein in pathological inclusions

21 January 2018

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0964-X

In vivo demonstration that alpha-synuclein oligomers are toxic

21 January 2018

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Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody

21 January 2018

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Changes in the solubility and phosphorylation of α-synuclein over the course of Parkinson's disease.

21 January 2018

1 reference

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Accumulation of Insoluble α-Synuclein in Dementia with Lewy Bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0964-X

10.1007/S00401-012-0964-X

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

2 September 2017

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