(Q38415577)

English

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

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Europe PubMed Central

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2 September 2017

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1. (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

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Julià Blanco

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Beatriz Mothe

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Maria Carmen Puertas

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María C Puertas

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Jorge Carrillo

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Javier Martinez-Picado

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Javier Martinez-Picado

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Christian Brander

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Christian Brander

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Felipe García

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Agathe León

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José Alcamí

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Bonaventura Clotet Sala

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Bonaventura Clotet

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Mª Ángeles Muñoz-Fernández

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María Ángeles Muñoz-Fernández

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José Luis Jiménez

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José Luis Jiménez

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Mariano Esteban

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Mariano Esteban

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Beatriz Perdiguero

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Beatriz Perdiguero

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Juan García-Arriaza

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Juan García-Arriaza

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Carmen E Gómez

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Carmen E Gómez

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Juan Carlos López Bernaldo de Quirós

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Juan Carlos López Bernaldo de Quirós

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Judit Pich

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Joan Albert Arnaiz

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Joan Albert Arnaiz

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Josep Maria Gatell

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Jose M Gatell

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Norma I Rallón

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Norma Rallón

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Montserrat Plana

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Montserrat Plana

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author name string

Nuria Climent

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Miriam Rosàs

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Nuria Gonzalez

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Carmen Alvarez-Fernández

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Sonsoles Sánchez-Palomino

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Alberto C Guardo

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José Peña

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José M Benito

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RISVAC-03 Study Group

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publication date

26 February 2015

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2 September 2017

Journal of Antimicrobial Chemotherapy

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2 September 2017

70

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2 September 2017

6

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1833-1842

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2 September 2017

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Dynamics of viral load rebound and immunological changes after stopping effective antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection

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https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

A therapeutic dendritic cell-based vaccine for HIV-1 infection

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication

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https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

1 reference

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21 January 2018

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.

1 reference

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21 January 2018

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2014).

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1BX08 gp120 and HIV-1(IIIB) Gag-Pol-Nef proteins of clade B.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Definition of the viral targets of protective HIV-1-specific T cell responses

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Immunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Broadly cross-neutralizing antibodies in HIV-1 patients with undetectable viremia

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Clinical applications of attenuated MVA poxvirus strain.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Therapeutic vaccines against HIV infection

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA) (author's transl)

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

MVA-nef induces HIV-1-specific polyfunctional and proliferative T-cell responses revealed by the combination of short- and long-term immune assays.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Expansion and diversification of virus-specific T cells following immunization of human immunodeficiency virus type 1 (HIV-1)-infected individuals with a recombinant modified vaccinia virus Ankara/HIV-1 Gag vaccine.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Safety and tolerability of recombinant modified vaccinia virus Ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Long-term Clinical Follow-up, without Antiretroviral Therapy, of Patients with Chronic HIV-1 Infection with Good Virological Response to Structured Treatment Interruption

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKV046

21 January 2018

Therapeutic Immunization with Dendritic Cells Loaded with Heat‐Inactivated Autologous HIV‐1 in Patients with Chronic HIV‐1 Infection

1 reference

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21 January 2018

Biphasic decline of CD4 cell count during scheduled treatment interruptions

1 reference

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CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

1 reference

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21 January 2018

Identifiers

10.1093/JAC/DKV046

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

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