(Q38428730)

English

Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis

scientific article published on 07 February 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 September 2017

Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

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endoplasmic reticulum

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Hee-Sun Moon

1

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Boyun Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

HyeRan Gwak

3

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Dong Hoon Suh

4

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Yong Sang Song

5

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

language of work or name

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based on heuristic

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publication date

7 February 2015

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Europe PubMed Central

PubMed publication ID

3 September 2017

Molecular Carcinogenesis

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Europe PubMed Central

PubMed publication ID

3 September 2017

55

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Europe PubMed Central

PubMed publication ID

3 September 2017

4

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Europe PubMed Central

PubMed publication ID

3 September 2017

346-356

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Europe PubMed Central

PubMed publication ID

3 September 2017

Cellular and molecular mechanisms of metformin: an overview

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin--mode of action and clinical implications for diabetes and cancer

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Use of metformin and the risk of ovarian cancer: a case-control analysis

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin intake is associated with better survival in ovarian cancer: a case-control study

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

In vitro metformin anti-neoplastic activity in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Induction of apoptosis by metformin in epithelial ovarian cancer: involvement of the Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin targets ovarian cancer stem cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer cultures

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Self-eating and self-killing: crosstalk between autophagy and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

The role of the unfolded protein response in tumour development: friend or foe?

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Endoplasmic reticulum stress and autophagy as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin targets c-MYC oncogene to prevent prostate cancer.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Relevance of the OCT1 transporter to the antineoplastic effect of biguanides

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Autophagy is activated for cell survival after endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Autophagy and cancer

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

ApoG2 induces ER stress-dependent apoptosis in gastric cancer cells in vitro and its real-time evaluation by bioluminescence imaging in vivo

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

The role of autophagy in cancer: therapeutic implications

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Unfolded protein response to autophagy as a promising druggable target for anticancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.22284

21 January 2018

Identifiers

10.1002/MC.22284

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

release_rpw2svglvbhcxluqouj6dvkyyi

1 reference

https://api.fatcat.wiki/v0/release/rpw2svglvbhcxluqouj6dvkyyi

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

ResearchGate publication ID

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