(Q38451245)

3 September 2017

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title

Cellular and molecular mechanisms of statins: an update on pleiotropic effects (English)

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3 September 2017

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Mamoru Satoh

1

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3 September 2017

Yuji Takahashi

2

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3 September 2017

Tsuyoshi Tabuchi

3

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3 September 2017

Yoshitaka Minami

4

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3 September 2017

Makiko Tamada

5

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3 September 2017

Kan Takahashi

6

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3 September 2017

Tomonori Itoh

7

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3 September 2017

Yoshihiro Morino

8

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3 September 2017

Motoyuki Nakamura

9

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3 September 2017

language of work or name

English

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publication date

1 July 2015

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3 September 2017

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3 September 2017

volume

129

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3 September 2017

issue

2

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3 September 2017

page(s)

93-105

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Inflammation in atherosclerosis

3 September 2017

cites work

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21 January 2018

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Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study

21 January 2018

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The effects of atorvastatin on the occurrence of postoperative atrial fibrillation after off-pump coronary artery bypass grafting surgery

21 January 2018

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Effects of rosuvastatin on atrial fibrillation occurrence: ancillary results of the GISSI-HF trial

21 January 2018

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Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

21 January 2018

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Up-regulation of hepatic low-density lipoprotein receptor-related protein 1: a possible novel mechanism of antiatherogenic activity of hydroxymethylglutaryl-coenzyme A reductase inhibitor Atorvastatin and hepatic LRP1 expression.

21 January 2018

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Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

21 January 2018

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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

21 January 2018

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Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

21 January 2018

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Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre ra

21 January 2018

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The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

21 January 2018

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Intensive versus moderate lipid lowering with statins after acute coronary syndromes

21 January 2018

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Intensive lipid lowering with atorvastatin in patients with stable coronary disease

21 January 2018

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Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: results from the PROVE IT-TIMI 22 trial

21 January 2018

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Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study

21 January 2018

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High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study

21 January 2018

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Efficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coronary intervention: results of the ARMYDA-RECAPTURE (Atorvastatin for Reduction of Myocardial Damage During Angioplasty) Randomized Trial.

21 January 2018

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Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

21 January 2018

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Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults

21 January 2018

1 reference

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Prognostic value of coronary vascular endothelial dysfunction

21 January 2018

1 reference

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Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

21 January 2018

1 reference

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Minimally modified low density lipoprotein stimulates monocyte endothelial interactions

21 January 2018

1 reference

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Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells

21 January 2018

1 reference

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Isolation of putative progenitor endothelial cells for angiogenesis

21 January 2018

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Circulating endothelial progenitor cells and cardiovascular outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

21 January 2018

1 reference

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Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration

21 January 2018

1 reference

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Switching and signaling at the telomere

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Effect of intensive lipid-lowering therapy on telomere erosion in endothelial progenitor cells obtained from patients with coronary artery disease

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Toll-like receptors and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

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The toll of innate immunity on microbial pathogens

21 January 2018

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Local expression of Toll-like receptor 4 at the site of ruptured plaques in patients with acute myocardial infarction

21 January 2018

1 reference

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

C-reactive protein levels and outcomes after statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Differential effects of statins on relevant functions of human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Differential responsiveness of early- and late-passage endothelial cells to shear stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Vascular cell senescence: contribution to atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Emerging roles of SIRT1 in vascular endothelial homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Roles of SIRT1 in high glucose-induced endothelial impairment: association with diabetic atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Role of Toll like receptor signaling pathway in ischemic coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Sensing damage by the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

NLRP3 inflammasome activation in coronary artery disease: results from prospective and randomized study of treatment with atorvastatin or rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Regulation of apoptosis by alternative pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

miRNAs regulate miRNAs: coordinated transcriptional and post-transcriptional regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Clustering and conservation patterns of human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Expression of let-7i is associated with Toll-like receptor 4 signal in coronary artery disease: effect of statins on let-7i and Toll-like receptor 4 signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Active metabolite of atorvastatin inhibits membrane cholesterol domain formation by an antioxidant mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Cellular antioxidant effects of atorvastatin in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

miR-34a repression of SIRT1 regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

MiR-34, SIRT1 and p53: the feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for ‘pleiotropic’ functions of statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20150027

21 January 2018

Identifiers

DOI

10.1042/CS20150027

1 reference

3 September 2017

1 reference