(Q38458728)

3 September 2017

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title

Pseudoproteases: mechanisms and function (English)

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3 September 2017

Simone L Reynolds

1

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3 September 2017

Katja Fischer

series ordinal

2

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3 September 2017

language of work or name

English

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publication date

1 May 2015

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3 September 2017

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3 September 2017

volume

468

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3 September 2017

issue

1

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3 September 2017

page(s)

17-24

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Inactive enzyme-homologues find new function in regulatory processes

3 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Sequence and structural differences between enzyme and nonenzyme homologs

21 January 2018

1 reference

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Understanding the functional roles of amino acid residues in enzyme catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

A serine proteinase homologue, SPH-3, plays a central role in insect immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Covalent structure of human haptoglobin: a serine protease homolog

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20141506

A multigene family of inactivated cysteine proteases in Sarcoptes scabiei.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20141506

Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Structural mechanisms of inactivation in scabies mite serine protease paralogues

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20141506

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Mechanisms for a novel immune evasion strategy in the scabies mite sarcoptes scabiei: a multigene family of inactivated serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Cockroach allergen Bla g 2: an unusual aspartic proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Isolation, gene cloning and expression profile of a pathogen recognition protein: a serine proteinase homolog (Sp-SPH) involved in the antibacterial response in the crab Scylla paramamosain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

The proPO-system: pros and cons for its role in invertebrate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Expression of a serine proteinase homolog prophenoloxidase-activating factor from the blue crab, Callinectes sapidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

The clip-domain family of serine proteinases in arthropods

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20141506

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Scabies mite inactivated serine protease paralogs inhibit the human complement system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Characterization of a serine protease homologous to house dust mite group 3 allergens from the scabies mite Sarcoptes scabiei

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

A caspase-like decoy molecule enhances the activity of a paralogous caspase in the yellow fever mosquito, Aedes aegypti

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Cellular mechanisms controlling caspase activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

A unified model for apical caspase activation

21 January 2018

1 reference

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Activation of caspases-8 and -10 by FLIP(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Mechanism of procaspase-8 activation by c-FLIPL

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Amino acid sequence of CAP37, a human neutrophil granule-derived antibacterial and monocyte-specific chemotactic glycoprotein structurally similar to neutrophil elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Covalent structure of two novel neutrophile leucocyte-derived proteins of porcine and human origin. Neutrophile elastase homologues with strong monocyte and fibroblast chemotactic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Structure of HBP, a multifunctional protein with a serine proteinase fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Structure of the haptoglobin-haemoglobin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Identification of the haemoglobin scavenger receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Enzyme promiscuity: a mechanistic and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

An evolutionary biochemist's perspective on promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Protein promiscuity and its implications for biotechnology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

New insights about enzyme evolution from large scale studies of sequence and structure relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Enzyme promiscuity: engine of evolutionary innovation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Protein dynamism and evolvability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

What makes an enzyme promiscuous?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Cleavage entropy as quantitative measure of protease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active Site

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Evolution of the multifunctional protein tyrosine phosphatase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141506

21 January 2018

Identifiers

DOI

10.1042/BJ20141506

1 reference

3 September 2017

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