(Q38473587)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

main subject

Plasmodium falciparum

0 references

author

Andrzej Lewandowicz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Andrzej Lewandowicz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Kami Kim

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Gary B. Evans

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Richard Furneaux

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

13

Vern L Schramm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

6

Peter C Tyler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Erika A Taylor Ringia

3

object named as

Erika A Taylor Ringia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

10

Gavin F Painter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

11

Dirk H Lenz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

author name string

Li-Min Ting

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Olga V Zubkova

8

1 reference

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13 January 2020

Simon Mee

9

1 reference

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13 January 2020

language of work or name

English

0 references

publication date

16 June 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

13 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

issue

34

1 reference

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13 January 2020

page(s)

30320-30328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15961383%20AND%20SRC:MED&resulttype=core&format=json

Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

13 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2′-deoxyguanosine in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Imino-C-nucleoside synthesis: heteroaryl lithium carbanion additions to a carbohydrate cyclic imine and nitrone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Structural analyses reveal two distinct families of nucleoside phosphorylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Atomic motion in enzymatic reaction coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200

Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505033200