(Q38508018)

3 September 2017

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species (English)

1 reference

3 September 2017

0 references

Jane Z Reed

5

0 references

Denis Fourches

object named as

Denis Fourches

1

0 references

Alexander Tropsha

6

object named as

Alexander Tropsha

1 reference

3 September 2017

Julie C Barnes

2

1 reference

3 September 2017

Nicola C Day

3

1 reference

3 September 2017

Paul Bradley

4

1 reference

3 September 2017

language of work or name

1 reference

1 January 2010

1 reference

Chemical Research in Toxicology

3 September 2017

1 reference

3 September 2017

23

1 reference

3 September 2017

1

1 reference

3 September 2017

171-183

1 reference

In silico prediction of drug safety: despite progress there is abundant room for improvement

3 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Building a chemical space based on fragment descriptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Predictive QSAR modeling workflow, model applicability domains, and virtual screening

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Applying mechanisms of chemical toxicity to predict drug safety

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Predictive value of in vitro safety studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

In vitro methods to study chemically-induced hepatotoxicity: a literature review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

In silico models for the prediction of dose-dependent human hepatotoxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Concordance of the toxicity of pharmaceuticals in humans and in animals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

The predictivity of the toxicity of pharmaceuticals in humans from animal data--an interim assessment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Hepatotoxicity in drug development: detection, significance and solutions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Acute hepatitis following administration of fansidar

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Critical assessment of QSAR models of environmental toxicity against Tetrahymena pyriformis: focusing on applicability domain and overfitting by variable selection

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Cellular imaging predictions of clinical drug-induced liver injury

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Computational chemistry approach for the early detection of drug-induced idiosyncratic liver toxicity.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Drug-induced liver injury: summary of a single topic clinical research conference

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Substructural fragments: an universal language to encode reactions, molecular and supramolecular structures

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850112

Drug-induced liver injury

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20014752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/TX900326K

1 reference

3 September 2017

1 reference

3 September 2017

PubMed publication ID

20014752

1 reference