(Q38545041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

review article

1 reference

title

Medicinal Chemistry: Insights into the Development of Novel H2S Donors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

Armando Pacheco

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Ming Xian

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

publication date

1 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

Handbook of experimental pharmacology

19 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

365-388

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

The possible role of hydrogen sulfide as an endogenous neuromodulator.

19 February 2020

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Clarifying the real bioactive constituents of garlic

31 March 2020

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Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis

31 March 2020

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Hydrogen sulphide vasodilates human pulmonary arteries: a possible role in pulmonary hypertension?

31 March 2020

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Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells.

31 March 2020

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Hydrogen sulfide mediates the vasoactivity of garlic

31 March 2020

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Role of hydrogen sulfide in acute pancreatitis and associated lung injury

31 March 2020

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H2S induces a suspended animation-like state in mice

31 March 2020

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Synthesis and biological effects of hydrogen sulfide (H2S): development of H2S-releasing drugs as pharmaceuticals

31 March 2020

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Hydrogen sulfide mediates cardioprotection through Nrf2 signaling

31 March 2020

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Novel insights into hydrogen sulfide--mediated cytoprotection.

31 March 2020

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Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice

31 March 2020

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Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

31 March 2020

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NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model

31 March 2020

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Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma

31 March 2020

1 reference

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S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions

31 March 2020

1 reference

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S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway

31 March 2020

1 reference

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Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation.

31 March 2020

1 reference

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Passive loss of hydrogen sulfide in biological experiments

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Light-induced hydrogen sulfide release from "caged" gem-dithiols.

31 March 2020

1 reference

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5-Amino-2-hydroxybenzoic Acid 4-(5-Thioxo-5H-[1,2]dithiol-3yl)-phenyl Ester (ATB-429), a Hydrogen Sulfide-Releasing Derivative of Mesalamine, Exerts Antinociceptive Effects in a Model of Postinflammatory Hypersensitivity

31 March 2020

1 reference

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Crucial role of copper in detection of metal-coordinating odorants

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

The toxicity of hydrogen sulphide and other sulphides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

An open trial of high-dosage antioxidants in early Parkinson's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channel

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

S-aroylthiooximes: a facile route to hydrogen sulfide releasing compounds with structure-dependent release kinetics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide as a gasotransmitter

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Design and synthesis of polymeric hydrogen sulfide donors

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

S-Allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity, early markers of oxidative stress and mitochondrial dysfunction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice

31 March 2020

1 reference

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Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models.

31 March 2020

1 reference

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Hydrogen sulfide: neurophysiology and neuropathology.

31 March 2020

1 reference

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Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide

31 March 2020

1 reference

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Hydrogen sulfide dilates rat mesenteric arteries by activating endothelial large-conductance Ca²⁺-activated K⁺ channels and smooth muscle Ca²⁺ sparks

31 March 2020

1 reference

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Endogenous production of hydrogen sulfide in mammals

31 March 2020

1 reference

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Anti-inflammatory agents as cancer therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Anti-cancer activity of new designer hydrogen sulfide-donating hybrids

31 March 2020

1 reference

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Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

31 March 2020

1 reference

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Evidence for thiol-dependent production of oxygen radicals by 4-methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione (oltipraz) and 3H-1,2-dithiole-3-thione: possible relevance to the anticarcinogenic properties of 1,2-dithiole-3-thiones

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

S-Allyl-L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide protects neurons from oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

NOSH-Aspirin: A Novel Nitric Oxide-Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide chemical biology: pathophysiological roles and detection

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low-density lipoprotein

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Chemical foundations of hydrogen sulfide biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide and cell signaling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulphide: novel opportunity for drug discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulphide: biopharmacological roles in the cardiovascular system and pharmaceutical perspectives

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulphide is pro-inflammatory in haemorrhagic shock

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Molecular pathophysiology of Parkinson's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Chemical aspects of hydrogen sulfide measurements in physiological samples

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Prevention of liver damage by aged garlic extract and its components in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

A practical look at the chemistry and biology of hydrogen sulfide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Evolutionary and comparative aspects of nitric oxide, carbon monoxide and hydrogen sulfide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol-induced cardiotoxicity in rats: a histopathological study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Persulfide reactivity in the detection of protein s-sulfhydration.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Synthesis and evaluation of phosphorodithioate-based hydrogen sulfide donors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

H₂S signalling through protein sulfhydration and beyond

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide in biochemistry and medicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), more than meets the eye: a critical review

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

New biologically active hydrogen sulfide donors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Development of a highly selective fluorescence probe for hydrogen sulfide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Role of garlic in the prevention of ischemia-reperfusion injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Pharmacological profile of a novel H(2)S-releasing aspirin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Therapeutic potential of new hydrogen sulfide-releasing hybrids.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulphide and its therapeutic potential

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide: a gasotransmitter of clinical relevance

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Sulfhydration mediates neuroprotective actions of parkin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Gastrointestinal Safety and Anti-Inflammatory Effects of a Hydrogen Sulfide–Releasing Diclofenac Derivative in the Rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Dithiolethiones for cancer chemoprevention: where do we stand?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Detection of protein S-sulfhydration by a tag-switch technique.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Cysteine-activated hydrogen sulfide (H2S) donors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Controllable hydrogen sulfide donors and their activity against myocardial ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Thiol-activated gem-dithiols: a new class of controllable hydrogen sulfide donors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-18144-8_18

Thioglycine and l-thiovaline: Biologically active H2S-donors

31 March 2020

1 reference

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10.1007/978-3-319-18144-8_18

31 March 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26162844%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference