(Q38550956)

4 September 2017

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title

Guarding the frontiers: the biology of type III interferons (English)

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4 September 2017

Andreas Wack

1

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Rune Hartmann

object named as

Rune Hartmann

series ordinal

3

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author name string

Ewa Terczyńska-Dyla

series ordinal

2

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PubMed ID

26194286

4 September 2017

language of work or name

English

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publication date

1 July 2015

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4 September 2017

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4 September 2017

16

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4 September 2017

8

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4 September 2017

802-809

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Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression

4 September 2017

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12 December 2020

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

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12 December 2020

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

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12 December 2020

IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes

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12 December 2020

Pathogenic potential of interferon αβ in acute influenza infection

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12 December 2020

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity

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12 December 2020

IL28B in the era of direct-acting antivirals for hepatitis C.

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12 December 2020

Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway

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12 December 2020

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

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12 December 2020

Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

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12 December 2020

Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling

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12 December 2020

Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells

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12 December 2020

The role of transposable elements in the regulation of IFN-lambda1 gene expression

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12 December 2020

Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

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12 December 2020

IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression

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12 December 2020

Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

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12 December 2020

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

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12 December 2020

Persistent LCMV infection is controlled by blockade of type I interferon signaling

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12 December 2020

Transcriptional regulation of IFN-λ genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex

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12 December 2020

The Mediator complex and transcription regulation

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12 December 2020

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

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12 December 2020

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

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12 December 2020

The cumulative effects of known susceptibility variants to predict primary biliary cirrhosis risk

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12 December 2020

Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3.

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12 December 2020

Blockade of chronic type I interferon signaling to control persistent LCMV infection

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12 December 2020

Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis

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12 December 2020

Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases

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12 December 2020

Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma

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12 December 2020

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production.

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12 December 2020

Regulation of IFN-λ1 promoter activity (IFN-λ1/IL-29) in human airway epithelial cells.

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12 December 2020

NK cells require IL-28R for optimal in vivo activity

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12 December 2020

IFN-λ-mediated IL-12 production in macrophages induces IFN-γ production in human NK cells

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12 December 2020

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

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12 December 2020

Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses

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12 December 2020

Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

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12 December 2020

Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

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12 December 2020

Temporal and spatial resolution of type I and III interferon responses in vivo

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12 December 2020

Toll-like receptor expression and induction of type I and type III interferons in primary airway epithelial cells

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12 December 2020

An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity

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12 December 2020

Peroxisomes are signaling platforms for antiviral innate immunity

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12 December 2020

Does IL28B genotyping still have a role in the era of direct-acting antiviral therapy for chronic hepatitis C infection?

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12 December 2020

Will IL28B polymorphisms remain relevant to direct-acting antiviral treatment paradigms?

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12 December 2020

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia

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12 December 2020

Interferon-lambda: a new addition to an old family

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12 December 2020

Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses

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12 December 2020

Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis.

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12 December 2020

Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth

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12 December 2020

Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

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12 December 2020

Regulation of interferon lambda-1 (IFNL1/IFN-λ1/IL-29) expression in human colon epithelial cells

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12 December 2020

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

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12 December 2020

IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

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12 December 2020

Do lambda-IFNs IL28A and IL28B act on human natural killer cells?

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12 December 2020

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

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12 December 2020

A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

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12 December 2020

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

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12 December 2020

Interferon-λ in the context of viral infections: production, response and therapeutic implications

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12 December 2020

IFNL4-ΔG genotype is associated with slower viral clearance in hepatitis C, genotype-1 patients treated with sofosbuvir and ribavirin

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12 December 2020

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

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12 December 2020

Interferon induction and function at the mucosal surface

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12 December 2020

The IFNL3/4 ΔG variant increases susceptibility to cytomegalovirus retinitis among HIV-infected patients

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12 December 2020

IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells

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12 December 2020

Viral Infections Activate Types I and III Interferon Genes through a Common Mechanism

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12 December 2020

Interferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

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12 December 2020

Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent

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12 December 2020

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

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12 December 2020

Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection

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12 December 2020

Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo

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12 December 2020

Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections

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12 December 2020

IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo

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12 December 2020

IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease

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12 December 2020

Type I interferons in infectious disease

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12 December 2020

Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)

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12 December 2020

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.

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12 December 2020

IFN-lambda determines the intestinal epithelial antiviral host defense

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12 December 2020

Lymphocytes degranulation in liver in hepatitis C virus carriers is associated with IFNL4 polymorphisms and ALT levels

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12 December 2020

Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.

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12 December 2020

The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-lambda family

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12 December 2020

Modulation of human plasmacytoid DC function by IFN-lambda1 (IL-29)

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12 December 2020

Biological activity of interleukins-28 and -29: comparison with type I interferons

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12 December 2020

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

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12 December 2020

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

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12 December 2020

Human but not mouse hepatocytes respond to interferon-lambda in vivo

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12 December 2020

Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection

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12 December 2020

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

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12 December 2020

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

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12 December 2020

Evolutionary genetic dissection of human interferons

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12 December 2020

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

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12 December 2020

Faldaprevir and deleobuvir for HCV genotype 1 infection.

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12 December 2020

Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo

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12 December 2020

Global epidemiology of hepatitis C virus infection

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12 December 2020

Interferon-lambda as a new approach for treatment of allergic asthma?

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12 December 2020

IL-28, IL-29 and their class II cytokine receptor IL-28R

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12 December 2020

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

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12 December 2020

A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection

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12 December 2020

Disease-promoting effects of type I interferons in viral, bacterial, and coinfections

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12 December 2020

Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10

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12 December 2020

Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B.

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12 December 2020

Influence of IFNL3/4 polymorphisms on the incidence of cytomegalovirus infection after solid-organ transplantation

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12 December 2020

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

1 reference

12 December 2020

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

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12 December 2020

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

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12 December 2020

USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

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12 December 2020

Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo

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12 December 2020

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes

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12 December 2020

Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes

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12 December 2020

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

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12 December 2020

Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus

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12 December 2020

Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons

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12 December 2020

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12 December 2020

IL-28B is a key regulator of B- and T-cell vaccine responses against influenza

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12 December 2020

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

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Crossref

https://api.crossref.org/works/10.1038%2FNI.3212

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NI.3212

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4 September 2017

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1 reference

PubMed ID

26194286