(Q38558127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

2 references

20 October 2020

29 April 2021

Conservation of the Keap1-Nrf2 System: An Evolutionary Journey through Stressful Space and Time (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

20 October 2020

nuclear factor erythroid 2-related factor 2

1 reference

29 April 2021

Yuji Fuse

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Makoto Kobayashi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

language of work or name

English

0 references

publication date

9 March 2017

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

20 October 2020

29 April 2021

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

20 October 2020

29 April 2021

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

5 April 2020

copyright license

2 references

20 October 2020

29 April 2021

0 references

Molecular basis of the Keap1-Nrf2 system.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Toward clinical application of the Keap1-Nrf2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio)

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Mechanisms and functions of Nrf2 signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Small Maf proteins (MafF, MafG, MafK): History, structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Small Maf deficiency recapitulates the liver phenotypes of Nrf1- and Nrf2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The Yap family and its role in stress response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Identification and characterization of a Saccharomyces cerevisiae gene (PAR1) conferring resistance to iron chelators

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

H2O2 sensing through oxidation of the Yap1 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Peroxiredoxin-mediated redox regulation of the nuclear localization of Yap1, a transcription factor in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcriptional regulation of xenobiotic detoxification in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The SKN-1 amino-terminal arm is a DNA specificity segment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

MafT, a new member of the small Maf protein family in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2-dependent protection against acute sodium arsenite toxicity in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio)

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Conservation of the Nrf2-Mediated Gene Regulation of Proteasome Subunits and Glucose Metabolism in Zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The genome of the sea urchin Strongylocentrotus purpuratus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The octopus genome and the evolution of cephalopod neural and morphological novelties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The dynamic genome of Hydra

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Changing gears in Nrf1 research, from mechanisms of regulation to its role in disease and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

NFE2L3 (NRF3): the Cinderella of the Cap'n'Collar transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Molecular evolution of Keap1. Two Keap1 molecules with distinctive intervening region structures are conserved among fish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The African coelacanth genome provides insights into tetrapod evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The genome of the green anole lizard and a comparative analysis with birds and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Activation of NRF2 by nitrosative agents and H2O2 involves KEAP1 disulfide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Connecting genotypes, phenotypes and fitness: harnessing the power of CRISPR/Cas9 genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030436

Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and nrf-2.

21 January 2018

1 reference

12 December 2020

Control of Drosophila head segment identity by the bZIP homeotic gene cnc

1 reference

12 December 2020

Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal

1 reference

12 December 2020

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants

1 reference

12 December 2020

A cap 'n' collar protein isoform contains a selective Hox repressor function.

1 reference

12 December 2020

Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head.

1 reference

12 December 2020

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione

1 reference

12 December 2020

10.3390/MOLECULES22030436

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28282941%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference