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RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p.
scientific article published on May 2008
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scholarly article
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stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
title
RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
main subject
fluorouracil
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based on heuristic
inferred from title
author
Jason Hoskins
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
J Scott Butler
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
language of work or name
English
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publication date
1 May 2008
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Genetics
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
179
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
323-330
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
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Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo
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Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes
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6 September 2017
A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p
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Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation
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The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase
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The yeast nucleolar protein Cbf5p is involved in rRNA biosynthesis and interacts genetically with the RNA polymerase I transcription factor RRN3.
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6 September 2017
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Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation
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6 September 2017
Getting started with yeast
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6 September 2017
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6 September 2017
Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase
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6 September 2017
Interactions of transfer RNA pseudouridine synthases with RNAs substituted with fluorouracil
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The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae
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Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing
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23 June 2018
Incorporation of 5-fluorouracil into U2 and U6 snRNA inhibits mRNA precursor splicing.
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23 June 2018
Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells
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23 June 2018
Fragmentation of replicating chromosomes triggered by uracil in DNA.
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Modulation of 5-fluorouracil metabolism by thymidine. In vivo and in vitro studies on RNA-directed effects in rat liver and hepatoma
1 reference
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based on heuristic
inferred from PubMed ID database lookup
Reduced levels of 5,6-dihydrouridine in fluorouracil-containing transfer RNAs from Saccharomyces cerevisiae
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18493057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18493057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18493057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1534/GENETICS.107.082727
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PMCID
2390612
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed ID
18493057
1 reference
stated in
Europe PubMed Central
PMCID
2390612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18493057%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
ResearchGate publication ID
5357451
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