(Q38583023)

4 September 2017

title

Autoreactivity and the positive selection of B cells (English)

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4 September 2017

Rudolf Übelhart

1

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4 September 2017

Hassan Jumaa

series ordinal

2

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4 September 2017

language of work or name

English

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publication date

19 August 2015

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European Journal of Immunology

4 September 2017

published in

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4 September 2017

volume

45

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4 September 2017

issue

11

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4 September 2017

page(s)

2971-2977

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V(D)J recombination: molecular biology and regulation

4 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Sites and stages of autoreactive B cell activation and regulation.

21 January 2018

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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

21 January 2018

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Receptor editing in self-reactive bone marrow B cells

21 January 2018

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Receptor editing: an approach by autoreactive B cells to escape tolerance

21 January 2018

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

21 January 2018

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The surrogate light chain in B-cell development.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

Selection events operating at various stages in B cell development

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

The transient expression of pre-B cell receptors governs B cell development

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling

21 January 2018

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Signaling circuits in early B-cell development

21 January 2018

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Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of lambda 5 and stroma cell-associated heparan sulfate.

21 January 2018

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Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

Autoreactive B cell receptors mimic autonomous pre-B cell receptor signaling and induce proliferation of early B cells

21 January 2018

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Surrogate light chain-mediated interaction of a soluble pre-B cell receptor with adherent cell lines

21 January 2018

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Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions.

21 January 2018

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N-linked glycosylation selectively regulates autonomous precursor BCR function

21 January 2018

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The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling

21 January 2018

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Structural insight into pre-B cell receptor function

21 January 2018

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Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

21 January 2018

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Efficient generation of B lymphocytes by recognition of self-antigens

21 January 2018

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Receptor editing in lymphocyte development and central tolerance.

21 January 2018

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Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies.

21 January 2018

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Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.

21 January 2018

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Endogenous antigen tunes the responsiveness of naive B cells but not T cells

21 January 2018

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B-cell anergy: from transgenic models to naturally occurring anergic B cells?

21 January 2018

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Predominant autoantibody production by early human B cell precursors

21 January 2018

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B cell receptor signal strength determines B cell fate

21 January 2018

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Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

B cell development pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

IgD can largely substitute for loss of IgM function in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Follicular dendritic cells as accessory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Follicular dendritic cells help resting B cells to become effective antigen-presenting cells: induction of B7/BB1 and upregulation of major histocompatibility complex class II molecules

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201444622

B cells acquire antigen from target cells after synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Mature B cells class switched to IgD are autoreactive in healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Erratum: Responsiveness of B cells is regulated by the hinge region of IgD

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

Conventional light chains inhibit the autonomous signaling capacity of the B cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

7 January 2021

Surrogate-light-chain silencing is not critical for the limitation of pre-B cell expansion but is for the termination of constitutive signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

7 January 2021

Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

7 January 2021

IgD expression on B cells is more efficient than IgM but both receptors are functionally equivalent in up-regulation CD80/CD86 co-stimulatory molecules

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444622

7 January 2021

Identifiers

DOI

10.1002/EJI.201444622

1 reference

4 September 2017

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