(Q38583217)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Regulator of calcineurin 1 mediates pathological vascular wall remodeling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1

1 reference

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13 February 2020

Miguel R. Campanero

10

1 reference

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13 February 2020

María Lourdes Arbonés

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

Luis Jesús Jiménez Borreguero

13 February 2020

3

1 reference

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13 February 2020

Ana García-Redondo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Mercedes Salaices

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Juan Miguel Redondo

11

1 reference

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13 February 2020

author name string

Nerea Méndez-Barbero

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Mercè Roqué

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Laura Novensá

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Luis Vila

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

19 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

13 February 2020

published in

1 reference

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13 February 2020

volume

208

1 reference

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13 February 2020

issue

10

1 reference

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13 February 2020

page(s)

2125-2139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 February 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3182048

inferred from PubMed Central ID database lookup

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6 September 2017

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SVS practice guidelines for the care of patients with an abdominal aortic aneurysm: executive summary

6 September 2017

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The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice

6 September 2017

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Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

6 September 2017

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Digging in the "soil" of the aorta to understand the growth of abdominal aortic aneurysms

6 September 2017

1 reference

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Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point

6 September 2017

1 reference

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Rcan1 negatively regulates Fc epsilonRI-mediated signaling and mast cell function

6 September 2017

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NF-kappaB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1.

6 September 2017

1 reference

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Angiotensin-converting enzyme and vascular remodeling

6 September 2017

1 reference

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The role of the adventitia in vascular inflammation

6 September 2017

1 reference

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Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

6 September 2017

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

6 September 2017

1 reference

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Raf-1 is a binding partner of DSCR1

6 September 2017

1 reference

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Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.

6 September 2017

1 reference

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Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: role of angiotensin II.

6 September 2017

1 reference

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Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents

6 September 2017

1 reference

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Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Inhibitors of the calcineurin/NFAT pathway.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Drug-eluting stents: new era and new concerns

6 September 2017

1 reference

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Mouse models of abdominal aortic aneurysms

6 September 2017

1 reference

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Transcriptional regulation by calcium, calcineurin, and NFAT

6 September 2017

1 reference

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The critical role of c-Src and the Shc/Grb2/ERK2 signaling pathway in angiotensin II-dependent VSMC proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

NFAT signaling: choreographing the social lives of cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Vascular smooth muscle growth: autocrine growth mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Signaling events mediating the additive effects of oleic acid and angiotensin II on vascular smooth muscle cell migration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A conserved family of calcineurin regulators.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Manipulating immune responses with immunosuppressive agents that target NFAT.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Molecular and cellular phenotypes and their regulation in smooth muscle.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Analysis of the preexisting and nuclear forms of nuclear factor of activated T cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Regulation of differentiation of vascular smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Migration of smooth muscle and endothelial cells. Critical events in restenosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A hidden incoherent switch regulates RCAN1 in the calcineurin-NFAT signaling network.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Perspectives series: cell adhesion in vascular biology. Smooth muscle migration in atherosclerosis and restenosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

The intima. Soil for atherosclerosis and restenosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Understanding abdominal aortic aneurysm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

TGFbeta-induced GRK2 expression attenuates AngII-regulated vascular smooth muscle cell proliferation and migration

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Blockade of nuclear factor of activated T cells activation signaling suppresses balloon injury-induced neointima formation in a rat carotid artery model

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

A potential role for nuclear factor of activated T-cells in receptor tyrosine kinase and G-protein-coupled receptor agonist-induced cell proliferation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Serotonin potentiates angiotensin II--induced vascular smooth muscle cell proliferation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Bench to bedside: the development of rapamycin and its application to stent restenosis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

Two independent calcineurin-binding regions in the N-terminal domain of murine NF-ATx1 recruit calcineurin to murine NF-ATx1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182048

The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin

31 August 2018

1 reference

12 December 2020

Blockade of NFAT activation by the second calcineurin binding site

1 reference

12 December 2020

Induction of endothelin secretion by angiotensin II: effects on growth and synthetic activity of vascular smooth muscle cells

1 reference

12 December 2020

Secretory mechanism of immunoreactive endothelin in cultured bovine endothelial cells

1 reference

12 December 2020

Mouse model of femoral artery denudation injury associated with the rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils

1 reference

12 December 2020

Abdominal aortic aneurysm

1 reference

12 December 2020

Noninvasive measurement of abdominal aortic aneurysms in intact mice by a high-frequency ultrasound imaging system

1 reference

12 December 2020

ANG II-induced neointimal growth is mediated via cPLA2- and PLD2-activated Akt in balloon-injured rat carotid artery

1 reference

12 December 2020

Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes

1 reference

12 December 2020

Angiotensin II-induced progression of neointimal thickening in the balloon-injured rat carotid artery is AT1 receptor mediated

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20110503

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21930771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21930771

1 reference