(Q33308479)

25 July 2017

NF-kappaB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1. (English)

1 reference

25 July 2017

0 references

1 reference

1 reference

Yohan Oh

5

0 references

author name string

Eun Jung Lee

1

1 reference

25 July 2017

Su Ryeon Seo

2

1 reference

25 July 2017

Ji Won Um

3

1 reference

25 July 2017

Joongkyu Park

4

1 reference

25 July 2017

Kwang Chul Chung

6

1 reference

25 July 2017

language of work or name

English

0 references

publication date

4 December 2007

1 reference

Journal of Biological Chemistry

25 July 2017

1 reference

25 July 2017

283

1 reference

25 July 2017

3392-3400

1 reference

25 July 2017

6

1 reference

Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region

25 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Chromosome 21 and down syndrome: from genomics to pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Mutational analyses of the signals involved in the subcellular location of DSCR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Multiple roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product calcipressin 1 (or RCAN1) in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kappaB inducing kinase NIK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Nucleocytoplasmic shuttling and the control of NF-AT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Interaction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Raf-1 is a binding partner of DSCR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Pyrrolidine dithiocarbamate-induced neuronal cell death is mediated by Akt, casein kinase 2, c-Jun N-terminal kinase, and IkappaB kinase in embryonic hippocampal progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Overexpression of DSCR1 blocks zinc-induced neuronal cell death through the formation of nuclear aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

From calcium to NF-kappa B signaling pathways in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Protein aggregation and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

The neurobiologic consequences of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Loss of neurones from cortical and subcortical areas in Down's syndrome patients at middle age. Quantitative comparisons with younger Down's patients and patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Neuropathology in the Down's syndrome brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

The essential role of calcium in induction of the DSCR1 (ADAPT78) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Inhibitory effect of copper(II) on zinc(II)-induced aggregation of amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Neuroinflammatory signaling upregulation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

A century-old debate on protein aggregation and neurodegeneration enters the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706707200

21 January 2018

Identifiers

DOI

10.1074/JBC.M706707200

1 reference

25 July 2017

1 reference