(Q38584313)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

The potential of Beclin 1 as a therapeutic target for the treatment of breast cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Yoon Yang Jung

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Yu Kyung Lee

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

11 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

167-178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

Development by self-digestion: molecular mechanisms and biological functions of autophagy

23 February 2020

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Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

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Dynamics and diversity in autophagy mechanisms: lessons from yeast

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LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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Does autophagy contribute to cell death?

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The multifaceted roles of autophagy in tumors-implications for breast cancer

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The Beclin 1 network regulates autophagy and apoptosis

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Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

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A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

21 January 2018

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The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans

21 January 2018

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The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

21 January 2018

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14-3-3Tau regulates Beclin 1 and is required for autophagy

21 January 2018

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Use of chromatin immunoprecipitation to clone novel E2F target promoters

21 January 2018

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MicroRNA-modulated autophagic signaling networks in cancer

21 January 2018

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Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.

21 January 2018

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miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.

21 January 2018

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Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors

21 January 2018

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The in vitro cleavage of the hAtg proteins by cell death proteases

21 January 2018

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Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

21 January 2018

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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

21 January 2018

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Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.

21 January 2018

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Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1.

21 January 2018

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

21 January 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

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DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

21 January 2018

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JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

21 January 2018

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TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy

21 January 2018

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Parkin mono-ubiquitinates Bcl-2 and regulates autophagy

21 January 2018

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Differential interactions between Beclin 1 and Bcl-2 family members

21 January 2018

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ARF induces autophagy by virtue of interaction with Bcl-xl.

21 January 2018

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Endogenous HMGB1 regulates autophagy

21 January 2018

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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

21 January 2018

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The structural era of endocytosis

21 January 2018

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Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

21 January 2018

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Plasma membrane contributes to the formation of pre-autophagosomal structures

21 January 2018

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Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway

21 January 2018

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Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

21 January 2018

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Sorting through the roles of beclin 1 in microglia and neurodegeneration

21 January 2018

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PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

21 January 2018

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Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

21 January 2018

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Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

21 January 2018

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Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells

21 January 2018

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Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma

21 January 2018

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Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

1 reference

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Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.

21 January 2018

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The bone marrow niche, stem cells, and leukemia: impact of drugs, chemicals, and the environment

21 January 2018

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Dissecting the pathways that destabilize mutant p53: the proteasome or autophagy?

21 January 2018

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Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

21 January 2018

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Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer.

21 January 2018

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Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

21 January 2018

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Defective downregulation of receptor tyrosine kinases in cancer

21 January 2018

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Tetraploidy, aneuploidy and cancer

21 January 2018

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American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer

21 January 2018

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American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

21 January 2018

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Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24.

21 January 2018

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Amplification of a novel v-erbB-related gene in a human mammary carcinoma.

21 January 2018

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HER-2/neu oncogene protein and prognosis in breast cancer

21 January 2018

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Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer

21 January 2018

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21 January 2018

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Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer

21 January 2018

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Differences in autophagy-related activity by molecular subtype in triple-negative breast cancer

21 January 2018

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Expression of autophagy-related proteins according to androgen receptor and HER-2 status in estrogen receptor-negative breast cancer

21 January 2018

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Expression of autophagy-related markers beclin-1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer.

21 January 2018

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Metabolic interaction between cancer cells and stromal cells according to breast cancer molecular subtype.

21 January 2018

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P-cadherin signals through the laminin receptor α6β4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells.

21 January 2018

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ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

21 January 2018

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Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis.

21 January 2018

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Pleomorphic lobular carcinoma of the breast: its cell kinetics, expression of oncogenes and tumour suppressor genes compared with invasive ductal carcinomas and classical infiltrating lobular carcinomas

21 January 2018

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Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation

21 January 2018

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Regulation of estrogenic effects by beclin 1 in breast cancer cells

21 January 2018

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Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance

21 January 2018

1 reference

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BH3 mimetics activate multiple pro-autophagic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1085971

Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

21 January 2018

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A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum

21 January 2018

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Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy.

21 January 2018

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RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia

21 January 2018

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γ-Tocotrienol-induced autophagy in malignant mammary cancer cells

21 January 2018

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Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1085971

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

21 January 2018

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Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

21 January 2018

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Apoptosis and autophagy induction as mechanism of cancer prevention by naturally occurring dietary agents

21 January 2018

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Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival

21 January 2018

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Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab

21 January 2018

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Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer

21 January 2018

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The role of autophagy in cancer: therapeutic implications

21 January 2018

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Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification

21 January 2018

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10.1517/14728222.2016.1085971

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26357854%20AND%20SRC:MED&resulttype=core&format=json

release_hfprf6ro6zexdppiaalo2fmouy

23 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hfprf6ro6zexdppiaalo2fmouy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference