(Q33648384)

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Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells (English)

1 reference

Europe PubMed Central

28 July 2017

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Eeva-Liisa Eskelinen

7

object named as

Eeva-Liisa Eskelinen

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author name string

Byong Hoon Yoo

1

1 reference

Europe PubMed Central

28 July 2017

Xue Wu

2

1 reference

Europe PubMed Central

28 July 2017

Yongling Li

3

1 reference

Europe PubMed Central

28 July 2017

Mehnaaz Haniff

4

1 reference

Europe PubMed Central

28 July 2017

Takehiko Sasazuki

5

1 reference

Europe PubMed Central

28 July 2017

Senji Shirasawa

6

1 reference

Europe PubMed Central

28 July 2017

Kirill V Rosen

8

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

24 September 2009

1 reference

Europe PubMed Central

28 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

28 July 2017

285

1 reference

Europe PubMed Central

28 July 2017

8

1 reference

Europe PubMed Central

28 July 2017

5438-5449

1 reference

Europe PubMed Central

28 July 2017

Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Acquisition of anoikis resistance promotes the emergence of oncogenic K-ras mutations in colorectal cancer cells and stimulates their tumorigenicity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Recurrent KRAS codon 146 mutations in human colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Maturation of autophagic vacuoles in Mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Another way to die: autophagic programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Lysosomes and autophagy in cell death control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Autophagy in cell death: an innocent convict?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Calpain activity is generally elevated during transformation but has oncogene-specific biological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

The dark side of Ras: regulation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

The calpain system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Taking the study of cancer cell survival to a new dimension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Anoikis mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Understanding Ras: 'it ain't over 'til it's over'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Increasing complexity of Ras signal transduction: involvement of Rho family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Disruption of epithelial cell-matrix interactions induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Induction of cyclin D1 overexpression by activated ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

21 June 2018

ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Rho GTPases are over-expressed in human tumors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Overexpression of m-calpain in human colorectal adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820772

30 October 2018

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.046789

21 January 2018

Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19778902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19778902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19778902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.046789

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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