(Q38598522)

4 September 2017

Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy (English)

1 reference

4 September 2017

1 reference

2

Michael Lim

1 reference

4 September 2017

Andrew B Sharabi

1

1 reference

PubMed ID

26433823

4 September 2017

Theodore L DeWeese

series ordinal

3

1 reference

PubMed ID

26433823

4 September 2017

Charles G Drake

series ordinal

4

1 reference

4 September 2017

1 October 2015

1 reference

Lancet Oncology Commission

4 September 2017

1 reference

4 September 2017

16

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4 September 2017

13

1 reference

4 September 2017

e498-509

1 reference

The effects of therapeutic irradiation on lymphocytes and immunity

4 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Review of image-guided radiation therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Immune modulation by ionizing radiation and its implications for cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

[Antitumoral action of interferons and interleukins in combination with radiotherapy. Part I: immunologic basis]

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Breakthrough of the year 2013. Cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Immunotherapy earns its spot in the ranks of cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Nivolumab plus ipilimumab in advanced melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Whole body irradiation; radiobiology or medicine?

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Towards a systems understanding of MHC class I and MHC class II antigen presentation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

HMGB1 is an endogenous immune adjuvant released by necrotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Calreticulin exposure dictates the immunogenicity of cancer cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

The confluence of stereotactic ablative radiotherapy and tumor immunology

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Induction of apoptosis through the activation of SAPK/JNK followed by the expression of death receptor Fas in X-irradiated cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation and ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Decisions about dendritic cells: past, present, and future

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiotherapy promotes tumor-specific effector CD8+ T cells via dendritic cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Characterization of direct radiation-induced immune function and molecular signaling changes in an antigen presenting cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naive T-cell priming

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Danger - pathogen on the premises! Immunological tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

How dying cells alert the immune system to danger

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Induction of the expression of the interleukin-1 beta gene in mouse spleen by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiotherapy augments the immune response to prostate cancer in a time-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Maximizing tumor immunity with fractionated radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Selective changes in the immune profile of tumor-draining lymph nodes after different neoadjuvant chemoradiation regimens for locally advanced cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

The immunobiology of cancer immunosurveillance and immunoediting

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Immune privilege or privileged immunity?

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

PD-L1(hi) retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Age dependence of hematopoietic progenitor survival and chemokine family gene induction after gamma irradiation in bone marrow tissue in C3H/He mice

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Up-regulation of the pro-inflammatory chemokine CXCL16 is a common response of tumor cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation enhances regulatory T cell representation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Regulatory T cells and immune tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: a current perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Immunologic correlates of the abscopal effect in a patient with melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

PD-1 Restrains Radiotherapy-Induced Abscopal Effect.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Radiation as an immunological adjuvant: current evidence on dose and fractionation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900007-8

7 January 2021

10.1016/S1470-2045(15)00007-8

Identifiers

DOI

1 reference

4 September 2017

1 reference

PubMed ID

26433823