(Q38608077)

4 September 2017

Nanomedicine delivery: does protein corona route to the target or off road? (English)

1 reference

Francesca Baldelli Bombelli

4 September 2017

1 reference

Daniele Maiolo

1

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object named as

Francesca Baldelli Bombelli

5

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Pablo Del Pino

object named as

Pablo Del Pino

2

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Pierangelo Metrangolo

object named as

Pierangelo Metrangolo

3

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author name string

Wolfgang J Parak

4

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4 September 2017

16 October 2015

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4 September 2017

1 reference

4 September 2017

10

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4 September 2017

21

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4 September 2017

3231-3247

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The challenge to relate the physicochemical properties of colloidal nanoparticles to their cytotoxicity

4 September 2017

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Interaction of colloidal nanoparticles with their local environment: the (ionic) nanoenvironment around nanoparticles is different from bulk and determines the physico-chemical properties of the nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Bridge over troubled waters: understanding the synthetic and biological identities of engineered nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Polymer-coated nanoparticles interacting with proteins and cells: focusing on the sign of the net charge

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Combined atomic force microscopy and optical microscopy measurements as a method to investigate particle uptake by cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Detailed Identification of Plasma Proteins Adsorbed on Copolymer Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Time evolution of the nanoparticle protein corona.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Volumetric interpretation of protein adsorption: competition from mixtures and the Vroman effect

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Temperature: the "ignored" factor at the NanoBio interface.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

The yin of exofacial protein sulfhydryls and the yang of intracellular glutathione in in vitro transfection with SS14 bioreducible lipoplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Reversible versus irreversible binding of transferrin to polystyrene nanoparticles: soft and hard corona.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Surfactant titration of nanoparticle-protein corona.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

All-oxide Raman-active traps for light and matter: probing redox homeostasis model reactions in aqueous environment.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

In vivo integrity of polymer-coated gold nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Surface Functionalization of Nanoparticles with Polyethylene Glycol: Effects on Protein Adsorption and Cellular Uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Enhancement of in vitro translation by gold nanoparticle--DNA conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

The "sweet" side of the protein corona: effects of glycosylation on nanoparticle-cell interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Technical tip: high-resolution isolation of nanoparticle-protein corona complexes from physiological fluids.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

What the Cell “Sees” in Bionanoscience

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Protein binding modulates the cellular uptake of silver nanoparticles into human cells: implications for in vitro to in vivo extrapolations?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Understanding biophysicochemical interactions at the nano-bio interface

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanoparticle-blood interactions: the implications on solid tumour targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Characterization of the bionano interface and mapping extrinsic interactions of the corona of nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

The Evolution of the Protein Corona around Nanoparticles: A Test Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Magnetic nanoparticles to recover cellular organelles and study the time resolved nanoparticle-cell interactome throughout uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Biomolecular coronas provide the biological identity of nanosized materials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanoparticle exposure in animals can be visualized in the skin and analysed via skin biopsy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Antifouling coatings: recent developments in the design of surfaces that prevent fouling by proteins, bacteria, and marine organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Macromolecular therapeutics in cancer treatment: the EPR effect and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

What does physics have to do with cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Secreted biomolecules alter the biological identity and cellular interactions of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Colorimetric nanoplasmonic assay to determine purity and titrate extracellular vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Optimizing the properties of the protein corona surrounding nanoparticles for tuning payload release.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Structure-based programming of lymph-node targeting in molecular vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Corona-directed nucleic acid delivery into hepatic stellate cells for liver fibrosis therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

An instantaneous colorimetric protein assay based on spontaneous formation of a protein corona on gold nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Detection and identification of proteins using nanoparticle-fluorescent polymer 'chemical nose' sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Air-blood barrier translocation of tracheally instilled gold nanoparticles inversely depends on particle size

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Differential roles of the protein corona in the cellular uptake of nanoporous polymer particles by monocyte and macrophage cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Renal clearance of quantum dots

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Surface chemistry of gold nanoparticles mediates their exocytosis in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: comparison with conventional monocultures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Exosome encased spherical nucleic acid gold nanoparticle conjugates as potent microRNA regulation agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Preventing protein adsorption and macrophage uptake of gold nanoparticles via a hydrophobic shield

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Fabrication of corona-free nanoparticles with tunable hydrophobicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Novel zwitterionic-polymer-coated silica nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Charged gold nanoparticles with essentially zero serum protein adsorption in undiluted fetal bovine serum

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Monoclonal antibody-functionalized multilayered particles: targeting cancer cells in the presence of protein coronas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Kupffer cells are central in the removal of nanoparticles from the organism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Shape effects of filaments versus spherical particles in flow and drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Zwitterionic-coated "stealth" nanoparticles for biomedical applications: recent advances in countering biomolecular corona formation and uptake by the mononuclear phagocyte system

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Tissue-penetrating delivery of compounds and nanoparticles into tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Mapping protein binding sites on the biomolecular corona of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

A holistic approach to targeting disease with polymeric nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Transferrin coated nanoparticles: study of the bionano interface in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Exploiting the protein corona around gold nanorods for loading and triggered release

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Improvement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG-PLA micelle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanomechanics of surface DNA switches probed by captive contact angle.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Peptide imprinted polymer nanoparticles: a plastic antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Liposome-protein corona in a physiological environment: challenges and opportunities for targeted delivery of nanomedicines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Selective targeting capability acquired with a protein corona adsorbed on the surface of 1,2-dioleoyl-3-trimethylammonium propane/DNA nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

pH-sensitive nano-systems for drug delivery in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Principles in the design of ligand-targeted cancer therapeutics and imaging agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Physicochemical properties of protein-coated gold nanoparticles in biological fluids and cells before and after proteolytic digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Molecular organization and signal transduction at intermembrane junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Nanomedicine--challenge and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Control of Protein-Binding Kinetics on Synthetic Polymer Nanoparticles by Tuning Flexibility and Inducing Conformation Changes of Polymer Chains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

Personalized protein coronas: a “key” factor at the nanobiointerface

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.15.163

21 January 2018

Identifiers

DOI

10.2217/NNM.15.163

1 reference

4 September 2017

1 reference

PubMed ID

26470748