(Q38611877)

4 September 2017

Cdk4 regulates adult neural stem cell proliferation and differentiation in response to insulin-IRS2 signals (English)

1 reference

María Isabel Fariñas Gómez

4 September 2017

1 reference

12

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10 June 2020

author name string

Laura Chirivella

1

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10 June 2020

Martina Kirstein

2

1 reference

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10 June 2020

Sacri R Ferrón

3

1 reference

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10 June 2020

Ana Domingo-Muelas

4

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10 June 2020

Fabrice C Durupt

5

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10 June 2020

Carlos Acosta-Umanzor

6

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10 June 2020

Marifé Cano-Jaimez

7

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10 June 2020

Francisco Pérez-Sánchez

8

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10 June 2020

Mariano Barbacid

9

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10 June 2020

Sagrario Ortega

10

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10 June 2020

Deborah J Burks

11

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10 June 2020

publication date

20 August 2017

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4 September 2017

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10 June 2020

volume

35

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10 June 2020

issue

12

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10 June 2020

page(s)

2403-2416

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Paracrine regulation of neural stem cells in the subependymal zone

10 June 2020

cites work

1 reference

It takes a village: constructing the neurogenic niche

21 January 2018

1 reference

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

21 January 2018

1 reference

A mosaic world: puzzles revealed by adult neural stem cell heterogeneity

21 January 2018

1 reference

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

21 January 2018

1 reference

Isolation, culture and analysis of adult subependymal neural stem cells

21 January 2018

1 reference

IGF-I has a direct proliferative effect in adult hippocampal progenitor cells

21 January 2018

1 reference

Roles of insulin and transferrin in neural progenitor survival and proliferation

21 January 2018

1 reference

Insulin-like growth factor-1 promotes G(1)/S cell cycle progression through bidirectional regulation of cyclins and cyclin-dependent kinase inhibitors via the phosphatidylinositol 3-kinase/Akt pathway in developing rat cerebral cortex

21 January 2018

1 reference

IGF-II promotes stemness of neural restricted precursors.

21 January 2018

1 reference

Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors in vitro Following Neonatal Hypoxia-Ischemia

21 January 2018

1 reference

Insulin and IGF receptor signalling in neural-stem-cell homeostasis.

21 January 2018

1 reference

The IRS-signalling system during insulin and cytokine action

21 January 2018

1 reference

The twentieth century struggle to decipher insulin signalling

21 January 2018

1 reference

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

1 reference

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family.

21 January 2018

1 reference

Insulin signal transduction and glucose transport in human adipocytes: effects of obesity and low calorie diet

21 January 2018

1 reference

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

Plakoglobin expression and localization in zebrafish embryo development

21 January 2018

1 reference

Insulin receptor substrate 2 is a negative regulator of memory formation

21 January 2018

1 reference

Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity

21 January 2018

1 reference

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

21 January 2018

1 reference

IGF-I and FGF-2 coordinately enhance cyclin D1 and cyclin E-cdk2 association and activity to promote G1 progression in oligodendrocyte progenitor cells.

21 January 2018

1 reference

Mechanism of insulin-like growth factor I-mediated proliferation of adult neural progenitor cells: role of Akt.

21 January 2018

1 reference

FGF2 and insulin signaling converge to regulate cyclin D expression in multipotent neural stem cells.

21 January 2018

1 reference

Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity

21 January 2018

1 reference

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

21 January 2018

1 reference

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

21 January 2018

1 reference

A combined ex/in vivo assay to detect effects of exogenously added factors in neural stem cells.

21 January 2018

1 reference

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

21 January 2018

1 reference

Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis

21 January 2018

1 reference

Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians.

21 January 2018

1 reference

IRS proteins and the common path to diabetes

21 January 2018

1 reference

Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging.

21 January 2018

1 reference

Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells

21 January 2018

1 reference

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin

21 January 2018

1 reference

Cell cycle regulation of proliferation versus differentiation in the central nervous system.

21 January 2018

1 reference

Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.

21 January 2018

1 reference

Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

21 January 2018

1 reference

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

21 January 2018

1 reference

CDK4 is an essential insulin effector in adipocytes

21 January 2018

1 reference

IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

21 January 2018

1 reference

Mash1 specifies neurons and oligodendrocytes in the postnatal brain

21 January 2018

1 reference

Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord.

21 January 2018

1 reference

The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes.

21 January 2018

1 reference

Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis

21 January 2018

1 reference

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection

21 January 2018

1 reference

The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.

21 January 2018

1 reference

The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.

21 January 2018

1 reference

Delta-Notch signaling regulates oligodendrocyte specification.

21 January 2018

1 reference

Neurite growth promotion by nerve growth factor and insulin-like growth factor-1 in cultured adult sensory neurons: role of phosphoinositide 3-kinase and mitogen activated protein kinase.

21 January 2018

1 reference

Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.

21 January 2018

1 reference

Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain

21 January 2018

1 reference

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

21 January 2018

1 reference

The E2F transcriptional network: old acquaintances with new faces

21 January 2018

1 reference

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

21 January 2018

1 reference

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

21 January 2018

1 reference

Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression.

21 January 2018

1 reference

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

21 January 2018

1 reference

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.

21 January 2018

1 reference

Co-ordination of cell cycle and differentiation in the developing nervous system

21 January 2018

1 reference

Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

1 reference

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.2694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833887%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference