(Q38616265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

title

Targeting cellular senescence prevents age-related bone loss in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

corrigendum / erratum

Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice.

0 references

author

Sundeep Khosla

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Ming Xu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Jad G. Sfeir

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Mikolaj Ogrodnik

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

author name string

Joshua N Farr

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Megan M Weivoda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

David G Monroe

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Daniel G Fraser

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Jennifer L Onken

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Brittany A Negley

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Christine M Hachfeld

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Nathan K LeBrasseur

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Matthew T Drake

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Robert J Pignolo

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Tamar Pirtskhalava

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Tamara Tchkonia

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Merry Jo Oursler

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

James L Kirkland

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

language of work or name

English

0 references

publication date

21 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

page(s)

1072-1079

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.4385

28 March 2020

exact match

0 references

cites work

Low-dose dasatinib rescues cardiac function in Noonan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Identification of Senescent Cells in the Bone Microenvironment

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Targeting senescent cells enhances adipogenesis and metabolic function in old age

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Cellular Senescence and the Biology of Aging, Disease, and Frailty

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Quercetin: A flavonol with multifaceted therapeutic applications?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Clinical strategies and animal models for developing senolytic agents

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Cellular senescence and the senescent secretory phenotype in age-related chronic diseases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Histone deacetylase 3 is required for maintenance of bone mass during aging

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Isolation and culture of primary osteocytes from the long bones of skeletally mature and aged mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

A senescent cell bystander effect: senescence-induced senescence

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

The senescence-associated secretory phenotype: the dark side of tumor suppression

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Zoledronic acid and clinical fractures and mortality after hip fracture

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Cellular senescence: when bad things happen to good cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Merck &Co. drops osteoporosis drug odanacatib.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Cellular senescence in aging primates.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5657592

A crucial role for adipose tissue p53 in the regulation of insulin resistance

31 August 2018

1 reference

7 January 2021

1 reference

7 January 2021

Morphological and mechanical properties of caudal vertebrae in the SAMP6 mouse model of senile osteoporosis

1 reference

7 January 2021

An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments

1 reference

7 January 2021

Mice lacking the plasminogen activator inhibitor 1 are protected from trabecular bone loss induced by estrogen deficiency

1 reference

7 January 2021

Odanacatib: location and timing are everything

1 reference

7 January 2021

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.4385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28825716%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference