(Q42018166)

15 October 2017

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response (English)

1 reference

15 October 2017

0 references

1 reference

Diana Jurk

1

0 references

Viktor Korolchuk

object named as

Viktor Korolchuk

5

0 references

Christopher Thrasivoulou

object named as

Christopher Thrasivoulou

8

0 references

Thomas von Zglinicki

object named as

Thomas von Zglinicki

11

0 references

author name string

Chunfang Wang

2

1 reference

15 October 2017

Satomi Miwa

3

1 reference

15 October 2017

Mandy Maddick

4

1 reference

15 October 2017

Avgi Tsolou

6

1 reference

15 October 2017

Efstathios S Gonos

7

1 reference

15 October 2017

M Jill Saffrey

9

1 reference

15 October 2017

Kerry Cameron

10

1 reference

15 October 2017

12 September 2012

1 reference

15 October 2017

1 reference

15 October 2017

11

1 reference

15 October 2017

6

1 reference

15 October 2017

996-1004

1 reference

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

A senescent cell bystander effect: senescence-induced senescence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Gross energy metabolism in mice under late onset, short term caloric restriction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Immune system to brain signaling: neuropsychopharmacological implications.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Activation of nuclear factor-kappa B signalling promotes cellular senescence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Age-associated increase in heterochromatic marks in murine and primate tissues

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Cellular senescence: putting the paradoxes in perspective

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Adult-onset, short-term dietary restriction reduces cell senescence in mice.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Aging of cerebellar Purkinje cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Oxidative stress and altered mitochondrial function in neurodegenerative diseases: lessons from mouse models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Inflammatory networks during cellular senescence: causes and consequences

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Feedback between p21 and reactive oxygen production is necessary for cell senescence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

DNA damage foci in mitosis are devoid of 53BP1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Mitochondrial dysfunction contributes to oncogene-induced senescence.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Free radical induced oxidative damage to DNA: relation to brain aging and neurological disorders.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Vulnerability to ROS-induced cell death in ageing articular cartilage: the role of antioxidant enzyme activity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Ink4a/Arf expression is a biomarker of aging

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Free radicals and brain aging

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Does a sentinel or a subset of short telomeres determine replicative senescence?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Oxidants, oxidative stress and the biology of ageing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Mitochondrial dysfunction in neurodegenerative disorders

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Oxidative stress, caloric restriction, and aging

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

The increased density of p38 mitogen-activated protein kinase-immunoreactive microglia in the sensorimotor cortex of aged TgCRND8 mice is associated predominantly with smaller dense-core amyloid plaques.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Quantitative assessment of markers for cell senescence.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Reactive oxygen species, dietary restriction and neurotrophic factors in age-related loss of myenteric neurons.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Cellular senescence in aging primates.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533793

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2012.00870.X

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2012.00870.X

DNA damage response and cellular senescence in tissues of aging mice

21 January 2018

1 reference

12 December 2020

Measuring the redox state of cellular peroxiredoxins by immunoblotting

1 reference

12 December 2020

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

12 December 2020

Mid-life onset of dietary restriction extends life and prolongs cognitive functioning

1 reference

12 December 2020

10.1111/J.1474-9726.2012.00870.X

Identifiers

DOI

1 reference

release_sawdfnfvdjbhnpleqwf4t73kym

15 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sawdfnfvdjbhnpleqwf4t73kym

24 November 2022

mapped directly with Wikidata item

1 reference

15 October 2017

PubMed publication ID

22882466

1 reference