(Q38624930)

English

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

scientific article published on 21 September 2011

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain (English)

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

neuropathic pain

0 references

Theodore J. Price

13

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Nahum Sonenberg

11

object named as

Nahum Sonenberg

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

object named as

Arianna Lark

6

0 references

author name string

Ohannes K Melemedjian

1

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Marina N Asiedu

2

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Dipti V Tillu

3

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Raul Sanoja

4

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Jin Yan

5

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Arkady Khoutorsky

7

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Jessica Johnson

8

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Katherine A Peebles

9

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Talya Lepow

10

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Gregory Dussor

12

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

publication date

21 September 2011

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

70

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

https://scigraph.springernature.com/pub.10.1186/1744-8069-7-70

0 references

Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

mTOR: from growth signal integration to cancer, diabetes and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Metformin activates AMP kinase through inhibition of AMP deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Sodium channel Na v 1.7 immunoreactivity in painful human dental pulp and burning mouth syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Sodium channels in normal and pathological pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Metabolic regulation of neuronal plasticity by the energy sensor AMPK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Translating nociceptor sensitivity: the role of axonal protein synthesis in nociceptor physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

MAP kinase and pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Translational control of long-lasting synaptic plasticity and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Nav1.7 expression is increased in painful human dental pulp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Local translation in primary afferent fibers regulates nociception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

RNA transport and localized protein synthesis in neurological disorders and neural repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Mechanisms of Disease: neuropathic pain—a clinical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Translational regulatory mechanisms in persistent forms of synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Local protein synthesis during axon guidance and synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Neurotrophic factors and their receptors in human sensory neuropathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Quantitative assessment of tactile allodynia in the rat paw

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Antibodies to nerve growth factor reverse established tactile allodynia in rodent models of neuropathic pain without tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

6 September 2017

Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

14 September 2017

ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

14 September 2017

Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

14 September 2017

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

25 September 2017

Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

25 September 2017

Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

23 June 2018

Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

23 June 2018

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

23 June 2018

Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

23 June 2018

Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

A functional role for intra-axonal protein synthesis during axonal regeneration from adult sensory neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186752

31 August 2018

Substituted biaryl pyrazoles as sodium channel blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imidazopyridines: A novel class of hNav1.7 channel blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1744-8069-7-70

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38624930&oldid=2155585018"