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The emerging role of lncRNAs in cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
title
The emerging role of lncRNAs in cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
author
Maite Huarte
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
language of work or name
English
0 references
publication date
5 November 2015
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
published in
Nature Medicine
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
volume
21
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
page(s)
1253-1261
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
issue
11
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
exact match
https://scigraph.springernature.com/pub.10.1038/nm.3981
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Landscape of transcription in human cells
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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
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Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs.
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression
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Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a
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7 January 2021
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Non-coding RNAs in human disease
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Long non-coding RNAs: challenges for diagnosis and therapies
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Junk DNA and the long non-coding RNA twist in cancer genetics.
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PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer
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DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer
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lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.
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A long noncoding RNA connects c-Myc to tumor metabolism.
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MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
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7 January 2021
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MALAT1 -- a paradigm for long noncoding RNA function in cancer
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Crossref
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7 January 2021
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The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
1 reference
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Crossref
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ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
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The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites
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Crossref
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RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The landscape of long noncoding RNAs in the human transcriptome
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The landscape of somatic copy-number alteration across human cancers
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Crossref
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7 January 2021
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A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer
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7 January 2021
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Signatures of mutational processes in human cancer
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7 January 2021
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Non-coding recurrent mutations in chronic lymphocytic leukaemia
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Principles for the post-GWAS functional characterization of cancer risk loci
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The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation
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Polymorphisms in the H19 gene and the risk of bladder cancer
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7 January 2021
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The H19 non-coding RNA is essential for human tumor growth
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Crossref
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7 January 2021
based on heuristic
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The role of long non-coding RNAs in genome formatting and expression
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Crossref
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7 January 2021
based on heuristic
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Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the Chinese Han population
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Crossref
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Gitools: analysis and visualisation of genomic data using interactive heat-maps
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Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2
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Large non-coding RNAs: missing links in cancer?
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7 January 2021
based on heuristic
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Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
MYC regulates the non-coding transcriptome.
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Crossref
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7 January 2021
based on heuristic
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Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis
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Crossref
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7 January 2021
based on heuristic
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Androgen responsive intronic non-coding RNAs
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex
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Crossref
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7 January 2021
based on heuristic
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
lincRNAs act in the circuitry controlling pluripotency and differentiation
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Crossref
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7 January 2021
based on heuristic
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RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform
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7 January 2021
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RNA therapeutics: beyond RNA interference and antisense oligonucleotides
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An improved zinc-finger nuclease architecture for highly specific genome editing
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7 January 2021
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RNA-guided genetic silencing systems in bacteria and archaea
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7 January 2021
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Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9.
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7 January 2021
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Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development
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Crossref
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7 January 2021
based on heuristic
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Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus
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7 January 2021
based on heuristic
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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
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7 January 2021
based on heuristic
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The hallmarks of cancer: a long non-coding RNA point of view.
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7 January 2021
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LncRNA: a link between RNA and cancer
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7 January 2021
based on heuristic
inferred from DOI database lookup
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological roles of long noncoding RNAs: insight from knockout mice
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
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Crossref
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https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Xist RNA is a potent suppressor of hematologic cancer in mice
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The evolution of lncRNA repertoires and expression patterns in tetrapods
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https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
lincRNAs: genomics, evolution, and mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraconserved Elements in the Human Genome
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https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional differences in the long non-coding RNA hotair in mouse and human
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of Hotair leads to homeotic transformation and gene derepression
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p53 by MEG3 non-coding RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long noncoding RNAs as a novel component of the Myc transcriptional network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons from functional analysis of genome-wide association studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
PVT1 dependence in cancer with MYC copy-number increase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer epigenetics: from mechanism to therapy
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Crossref
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https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Long non-coding RNAs and chromatin modifiers: their place in the epigenetic code
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Crossref
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https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modular regulatory principles of large non-coding RNAs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long non-coding RNA HOTAIR in carcinogenesis and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long noncoding RNA as modular scaffold of histone modification complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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inferred from DOI database lookup
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Promiscuous RNA binding by Polycomb repressive complex 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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X-inactivation, imprinting, and long noncoding RNAs in health and disease
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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LincRNA-p21 suppresses target mRNA translation
1 reference
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reference URL
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7 January 2021
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Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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lncRNA directs cooperative epigenetic regulation downstream of chemokine signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
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A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
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A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Circular RNAs are a large class of animal RNAs with regulatory potency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
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Natural RNA circles function as efficient microRNA sponges
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
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Deletion of PTENP1 pseudogene in human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Exosomes as intercellular signalosomes and pharmacological effectors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Towards a therapy for Angelman syndrome by targeting a long non-coding RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
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MicroRNAs and other non-coding RNAs as targets for anticancer drug development
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translating dosage compensation to trisomy 21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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The genomic binding sites of a noncoding RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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Methods for comprehensive experimental identification of RNA-protein interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Principles of long noncoding RNA evolution derived from direct comparison of transcriptomes in 17 species.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
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7 January 2021
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MEG3 noncoding RNA: a tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.3981
retrieved
7 January 2021
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Identifiers
DOI
10.1038/NM.3981
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
PubMed ID
26540387
1 reference
stated in
Europe PubMed Central
PubMed ID
26540387
retrieved
4 September 2017
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