(Q38653648)

5 September 2017

Mechanical control of cardiac myofibroblasts (English)

1 reference

5 September 2017

0 references

3

Boris Hinz

1 reference

5 September 2017

Sander van Putten

1

1 reference

PubMed ID

26620422

5 September 2017

Yousef Shafieyan

series ordinal

2

1 reference

5 September 2017

24 November 2015

1 reference

Journal of Molecular and Cellular Cardiology

5 September 2017

1 reference

5 September 2017

93

1 reference

5 September 2017

133-142

1 reference

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

5 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The cardiac fibroblast: functional and electrophysiological considerations in healthy and diseased hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Abolishing myofibroblast arrhythmogeneicity by pharmacological ablation of α-smooth muscle actin containing stress fibers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Intramyocardial fibroblast myocyte communication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Arrhythmogenic implications of fibroblast-myocyte interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The cell biology of disease: cellular mechanisms of cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The cardiac fibroblast: therapeutic target in myocardial remodeling and failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Diastolic heart failure: mechanisms and controversies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac intercellular communication: are myocytes and fibroblasts fair-weather friends?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myocardial remodeling after infarction: the role of myofibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Function and fate of myofibroblasts after myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibroblasts and myofibroblasts: what are we talking about?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanotransduction in cardiac hypertrophy and failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myofibroblasts: trust your heart and let fate decide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Functional crosstalk between cardiac fibroblasts and adult cardiomyocytes by soluble mediators.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblast: the renaissance cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Molecular basis of physiological heart growth: fundamental concepts and new players

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibroblast-myocyte electrotonic coupling: does it occur in native cardiac tissue?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cell junctions in the specialized conduction system of the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The myofibroblast, multiple origins for major roles in normal and pathological tissue repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Origin, development, and differentiation of cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblast in development and wound healing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblasts: at the heart of myocardial remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Altered fibroblast function following myocardial infarction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Origins of cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibrocytes are associated with the fibrosis of coronary heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The role of fibrocytes in fibrotic diseases of the lungs and heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Bone marrow-derived cells contribute to infarct remodelling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Bone marrow-derived myofibroblasts contribute functionally to scar formation after myocardial infarction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Bone marrow-derived cells contribute to fibrosis in the chronically failing heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The origin of fibroblasts and mechanism of cardiac fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myofibroblasts and mechano-regulation of connective tissue remodelling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Formation and function of the myofibroblast during tissue repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Alpha-smooth muscle actin expression upregulates fibroblast contractile activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Reversible differentiation of myofibroblasts by MyoD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Reversal of myofibroblast differentiation: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Reversible and irreversible differentiation of cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cellular and molecular mechanisms in kidney fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Platelet-derived growth factor involvement in myocardial remodeling following infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Heart repair by reprogramming non-myocytes with cardiac transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TGF-β signaling in fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Transforming growth factor (TGF)-β signaling in cardiac remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Persistent phenotypic shift in cardiac fibroblasts: impact of transient renin angiotensin system inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The endothelin-aldosterone axis and cardiovascular diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Targeting Wnt signaling to improve wound healing after myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TGF-beta and bFGF affect the differentiation of proliferating porcine fibroblasts into myofibroblasts in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of alpha-smooth muscle actin, leading to reduction of wound contraction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Targeting the PDGF signaling pathway in tumor treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The pathogenesis of cardiac fibrosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Regulation of PDGF and its receptors in fibrotic diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The (dys)functional extracellular matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Novel regulators of cardiac inflammation: Matricellular proteins expand their repertoire

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Dynamic cell-cell and cell-ECM interactions in the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myocardial fibroblast-matrix interactions and potential therapeutic targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Contribution of extracellular matrix to the mechanical properties of the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The extracellular matrix: at the center of it all.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Effects of non-linearity on cell-ECM interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanoregulation of cardiac myofibroblast differentiation: implications for cardiac fibrosis and therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Substrate stiffness-modulated registry phase correlations in cardiomyocytes map structural order to coherent beating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

A role for matrix stiffness in the regulation of cardiac side population cell function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Signs of stress on soft surfaces : A commentary on: Cui, Y., F.M. Hameed, B. Yang, K. Lee, C.Q. Pan, S. Park, and M. Sheetz. 2015. Cyclic stretching of soft substrates induces spreading and growth. Nat Commun. 6:6333.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The myofibroblast: paradigm for a mechanically active cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Measurement of intramyocardial oxygen tension during cardiac surgery in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac performance as a function of intracellular oxygen tension in buffer-perfused hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

In vivo mitochondrial oxygen tension measured by a delayed fluorescence lifetime technique

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Sandwich enzyme-linked immunosorbent assays (SELISAs) quantitate and distinguish two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) in complex biological fluids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Depletion of TGF-β from fetal bovine serum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Use of synthetic serum-free medium for culture of human dermal fibroblasts to establish an experimental system similar to living dermis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Hypoxia impairs skin myofibroblast differentiation and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cell locomotion and focal adhesions are regulated by substrate flexibility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Evaluation of polydimethylsiloxane scaffolds with physiologically-relevant elastic moduli: interplay of substrate mechanics and surface chemistry effects on vascular smooth muscle cell response.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cell-matrix adhesions on poly(vinyl alcohol) hydrogels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Microengineered in vitro model of cardiac fibrosis through modulating myofibroblast mechanotransduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

In situ elasticity modulation with dynamic substrates to direct cell phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibroblast adaptation and stiffness matching to soft elastic substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Techniques for mechanical stimulation of cells in vitro: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Magnitude and duration of stretch modulate fibroblast remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Extracellular matrix of mechanically stretched cardiac fibroblasts improves viability and metabolic activity of ventricular cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cyclic mechanical stretch reduces myofibroblast differentiation of primary lung fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Effects of static and cyclic loading in regulating extracellular matrix synthesis by cardiovascular cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cyclical mechanical stretch modulates expression of collagen I and collagen III by PKC and tyrosine kinase in cardiac fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Differential roles of extracellular signal-regulated kinase 1/2 and p38MAPK in mechanical load-induced procollagen alpha1(I) gene expression in cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Interactions between TGFβ1 and cyclic strain in modulation of myofibroblastic differentiation of canine mitral valve interstitial cells in 3D culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The impact of substrate stiffness and mechanical loading on fibroblast-induced scaffold remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cyclic stretching of soft substrates induces spreading and growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Combining dynamic stretch and tunable stiffness to probe cell mechanobiology in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Substrate stress relaxation regulates cell spreading.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

A new lock-step mechanism of matrix remodelling based on subcellular contractile events.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Regulation of myofibroblast activities: calcium pulls some strings behind the scene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The mechanical environment modulates intracellular calcium oscillation activities of myofibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Biomechanics: cell research and applications for the next decade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

From mechanotransduction to extracellular matrix gene expression in fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Effects of low frequency cyclic mechanical stretching on osteoclastogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Molecular mechanisms of cellular mechanosensing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Tissue cells feel and respond to the stiffness of their substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Environmental sensing through focal adhesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The role of focal adhesion complexes in fibroblast mechanotransduction during scar formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Integrins, focal adhesions, and cardiac fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Integrins and the myocardium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Regulation of matrix assembly through rigidity-dependent fibronectin conformational changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Local force and geometry sensing regulate cell functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

It has to be the αv: myofibroblast integrins activate latent TGF-β1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Integrin-mediated regulation of TGFβ in fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Sensing substrate rigidity by mechanosensitive ion channels with stress fibers and focal adhesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanoregulation of cytoskeletal dynamics by TRP channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TRPV4 channel inhibits TGF-β1-induced proliferation of hepatic stellate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Cardiac fibroblasts have functional TRPV4 activated by 4alpha-phorbol 12,13-didecanoate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Substrate stiffness-regulated matrix metalloproteinase output in myocardial cells and cardiac fibroblasts: implications for myocardial fibrosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: role of TGF-β1-TAK1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Long-term treatment with fasudil improves bleomycin-induced pulmonary fibrosis and pulmonary hypertension via inhibition of Smad2/3 phosphorylation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Role of YAP/TAZ in mechanotransduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Matrix Rigidity Mediates TGFβ1-Induced Epithelial-Myofibroblast Transition by Controlling Cytoskeletal Organization and MRTF-A Localization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The role of the MRTF-A/SRF pathway in ocular fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The role of proteases in transforming growth factor-beta activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

TGFβ: a sleeping giant awoken by integrins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Matricellular proteins in cardiac adaptation and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Latent TGF-β structure and activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

The single-molecule mechanics of the latent TGF-β1 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Nonlinear elasticity in biological gels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Mesenchymal stem cell mechanobiology and emerging experimental platforms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

Matrix mechanics and regulation of the fibroblast phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2015.11.025

10.1016/J.YJMCC.2015.11.025

7 January 2021

Identifiers

DOI

1 reference

5 September 2017

1 reference

PubMed ID

26620422