(Q38672075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

anal squamous cell carcinoma

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Wayne A. Phillips

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Maria-Pia Bernardi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Samuel Y Ngan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Michael Michael

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

A Craig Lynch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Alexander G Heriot

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

1 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

Lancet Oncology Commission

2 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

e611-21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

Epidermoid cancer of the anus

2 March 2020

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7 January 2021

Surgical considerations in anal cancer

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7 January 2021

Anal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up

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7 January 2021

Trends in incidence of anal cancer in Denmark

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7 January 2021

Trends in anal cancer in Australia, 1982-2005.

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7 January 2021

Increasing incidence of squamous cell carcinoma of the anus in Scotland, 1975-2002.

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7 January 2021

Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America

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7 January 2021

Combined therapy for cancer of the anal canal: a follow-up report

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7 January 2021

Australasian Gastrointestinal Trials Group (AGITG) contouring atlas and planning guidelines for intensity-modulated radiotherapy in anal cancer.

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7 January 2021

Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin

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7 January 2021

Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial

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7 January 2021

Patterns of local disease failure and outcome after salvage surgery in patients with anal cancer

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7 January 2021

Management of Local Disease Relapse

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7 January 2021

Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer

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7 January 2021

Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis

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7 January 2021

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

1 reference

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7 January 2021

Establishment and characterization of the human SaTM-1 anal canal squamous cell carcinoma cell line derived from lymph node metastasis

1 reference

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7 January 2021

A mouse model for human anal cancer

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7 January 2021

Inhibition of mTOR reduces anal carcinogenesis in transgenic mouse model

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7 January 2021

Rapamycin inhibits anal carcinogenesis in two preclinical animal models

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7 January 2021

The biological properties of E6 and E7 oncoproteins from human papillomaviruses.

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7 January 2021

The next generation of HPV vaccines: nonavalent vaccine V503 on the horizon

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7 January 2021

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

1 reference

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7 January 2021

Human papillomavirus testing in the prevention of cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

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7 January 2021

The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

1 reference

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7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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7 January 2021

Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions

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7 January 2021

Anal cancer and human papillomaviruses

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7 January 2021

Malignant progression of anal intra-epithelial neoplasia

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7 January 2021

Malignant transformation of high-grade anal intraepithelial neoplasia.

1 reference

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7 January 2021

Human papillomavirus infection is transient in young women: a population-based cohort study

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7 January 2021

Papillomaviruses in human cancers

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7 January 2021

Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: critical role of duration of infection

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7 January 2021

Immune responses to human papillomavirus

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7 January 2021

Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes

1 reference

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7 January 2021

E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions

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7 January 2021

The blockade of immune checkpoints in cancer immunotherapy

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7 January 2021

Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin

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7 January 2021

Molecular biology of squamous cell carcinoma of the anus

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7 January 2021

Current understanding and potential immunotherapy for HIV-associated squamous cell carcinoma of the anus (SCCA).

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7 January 2021

Recurrent deletions of chromosomes 11q and 3p in anal canal carcinoma

1 reference

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7 January 2021

A recurrent pattern of chromosomal aberrations and immunophenotypic appearance defines anal squamous cell carcinomas

1 reference

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7 January 2021

Molecular biology of squamous cell carcinoma of the anus: a comparison of HIV-positive and HIV-negative patients.

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7 January 2021

Loss of heterozygosity and HIV infection in patients with anal squamous-cell carcinoma.

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7 January 2021

Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24

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7 January 2021

Allelic deletion at 11q23.3-q25 is an early event in cervical neoplasia

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7 January 2021

Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.

1 reference

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7 January 2021

Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review

1 reference

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7 January 2021

Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal

1 reference

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7 January 2021

Expression of epidermal growth factor receptor in squamous cell carcinomas of the anal canal is independent of gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation.

1 reference

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7 January 2021

Reduced expression of p21WAF1 is an indicator of malignant behaviour in anal carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Immunohistochemical analysis of p53 expression in anal squamous neoplasia

1 reference

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7 January 2021

Overexpression of p53 protein and outcome of patients treated with chemoradiation for carcinoma of the anal canal: a report of randomized trial RTOG 87-04. Radiation Therapy Oncology Group

1 reference

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7 January 2021

Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma

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7 January 2021

EGFR and cancer prognosis

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7 January 2021

EGFR antagonists in cancer treatment

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7 January 2021

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors?

1 reference

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7 January 2021

K-ras status in squamous cell anal carcinoma (SCC): it's time for target-oriented treatment?

1 reference

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7 January 2021

p16INK4A, p53, EGFR expression and KRAS mutation status in squamous cell cancers of the anus: correlation with outcomes following chemo-radiotherapy

1 reference

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7 January 2021

Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer

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7 January 2021

Targeting PI3 kinase/AKT/mTOR signaling in cancer.

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7 January 2021

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

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7 January 2021

PI3K signalling: the path to discovery and understanding.

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7 January 2021

The multiple roles of PTEN in tumor suppression

1 reference

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7 January 2021

Human Papillomavirus Type 16 E7 Up-regulates AKT Activity through the Retinoblastoma Protein

1 reference

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7 January 2021

Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract - a systematic review and meta-analysis.

1 reference

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7 January 2021

Is there a gain in chromosome 3q in the pathway to anal cancer?

1 reference

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7 January 2021

Prognostic significance of the bcl-2 apoptotic family of proteins in primary and recurrent cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Human papillomavirus type 16 E6 and E7 oncoproteins upregulate c-IAP2 gene expression and confer resistance to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Effects of human papillomavirus type 16 oncoproteins on survivin gene expression.

1 reference

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7 January 2021

High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Phase I study of YM155, a novel survivin suppressant, in patients with advanced solid tumors

1 reference

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7 January 2021

Hedgehog-Gli signalling and the growth of the brain.

1 reference

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7 January 2021

Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response.

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7 January 2021

Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner

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7 January 2021

Inhibition of vascular endothelial growth factor receptor signaling in angiogenic tumor vasculature

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https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

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https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Dominant role of HPV16 E7 in anal carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2815%2900292-2

7 January 2021

Lm-LLO-Based Immunotherapies and HPV-Associated Disease

1 reference

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7 January 2021

ADXS-HPV: a therapeutic Listeria vaccination targeting cervical cancers expressing the HPV E7 antigen

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7 January 2021

Phase 1 study of cetuximab in combination with 5-fluorouracil, cisplatin, and radiotherapy in patients with locally advanced anal canal carcinoma

1 reference

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7 January 2021

Low response rate after cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: long-term results of the UNICANCER ACCORD 16 phase II trial

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7 January 2021

Cetuximab-based treatment of metastatic anal cancer: correlation of response with KRAS mutational status.

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7 January 2021

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

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7 January 2021

Platinum-based chemotherapy plus cetuximab in head and neck cancer

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7 January 2021

10.1016/S1470-2045(15)00292-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26678214%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference