(Q38673425)

5 September 2017

title

Mechanisms involved in triggering rheumatoid arthritis (English)

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5 September 2017

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3

Lars Klareskog

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5 September 2017

4

Vivianne Malmström

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5 September 2017

1

Anca I Catrina

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5 September 2017

2

Vijay Joshua

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5 September 2017

publication date

1 January 2016

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5 September 2017

published in

Immunological Reviews

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5 September 2017

volume

269

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5 September 2017

issue

1

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5 September 2017

page(s)

162-174

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2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

5 September 2017

cites work

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

21 January 2018

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Mapping pathogenesis of arthritis through small animal models

21 January 2018

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Genetically distinct subsets within ANCA-associated vasculitis

21 January 2018

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Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis

21 January 2018

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A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination

21 January 2018

1 reference

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

21 January 2018

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Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

21 January 2018

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Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis

21 January 2018

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A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

21 January 2018

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Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis

21 January 2018

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Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.

21 January 2018

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Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

21 January 2018

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Cellular and humoral immunity in arthritis are profoundly influenced by the interaction between cigarette smoke effects and host HLA-DR and DQ genes.

21 January 2018

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Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis.

21 January 2018

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Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

21 January 2018

1 reference

Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors

21 January 2018

1 reference

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

21 January 2018

1 reference

Immunopathology of rheumatoid arthritis. Antikeratin antibodies precede the clinical disease

21 January 2018

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Comparison of threshold cutpoints and continuous measures of anti-cyclic citrullinated peptide antibodies in predicting future rheumatoid arthritis

21 January 2018

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Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis

21 January 2018

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Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

21 January 2018

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Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles

21 January 2018

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The immune geography of IgA induction and function

21 January 2018

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Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response

21 January 2018

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Normal structure, function, and histology of mucosa-associated lymphoid tissue

21 January 2018

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Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.

21 January 2018

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Effects of cigarette smoke on Toll-like receptor (TLR) activation of chronic obstructive pulmonary disease (COPD) macrophages.

21 January 2018

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Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome.

21 January 2018

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Whole cigarette smoke increased the expression of TLRs, HBDs, and proinflammory cytokines by human gingival epithelial cells through different signaling pathways

21 January 2018

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Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.

21 January 2018

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Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis.

21 January 2018

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Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis.

21 January 2018

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Cigarette smoke inhibits engulfment of apoptotic cells by macrophages through inhibition of actin rearrangement

21 January 2018

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Cigarette smoke extract enhances rhinovirus-induced toll-like receptor 3 expression and interleukin-8 secretion in A549 cells

21 January 2018

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Comparison of the respiratory microbiome in healthy nonsmokers and smokers

21 January 2018

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A novel microbiota stratification system predicts future exacerbations in bronchiectasis

21 January 2018

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Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

21 January 2018

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Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

21 January 2018

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Citrullination of proteins: a common posttranslational modification pathway induced by different nanoparticles in vitro and in vivo

21 January 2018

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Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

21 January 2018

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Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

21 January 2018

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Concomitant inhalation of cigarette smoke and aerosolized protein activates airway dendritic cells and induces allergic airway inflammation in a TLR-independent way.

21 January 2018

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Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease

21 January 2018

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Rheumatoid arthritis-associated autoantibodies in non-rheumatoid arthritis patients with mucosal inflammation: a case-control study.

21 January 2018

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Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?

21 January 2018

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Periodontitis in systemic rheumatic diseases

21 January 2018

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Expression of peptidylarginine deiminase-2 and -4, citrullinated proteins and anti-citrullinated protein antibodies in human gingiva

21 January 2018

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Influence of periodontal disease, Porphyromonas gingivalis and cigarette smoking on systemic anti-citrullinated peptide antibody titres.

21 January 2018

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CXCL13 expression and follicular dendritic cells in relation to B-cell infiltration in periodontal disease tissues

21 January 2018

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Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

21 January 2018

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Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis

21 January 2018

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Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD)

21 January 2018

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Porphyromonas gingivalis peptidylarginine deiminase, a key contributor in the pathogenesis of experimental periodontal disease and experimental arthritis

21 January 2018

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Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

21 January 2018

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Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

21 January 2018

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Loss of sex and age driven differences in the gut microbiome characterize arthritis-susceptible 0401 mice but not arthritis-resistant 0402 mice

21 January 2018

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Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

21 January 2018

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Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

21 January 2018

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The value of ultrasonography in predicting arthritis in auto-antibody positive arthralgia patients: a prospective cohort study

21 January 2018

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Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

21 January 2018

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IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies.

21 January 2018

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Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

21 January 2018

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Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies.

21 January 2018

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Citrullination is an inflammation-dependent process

21 January 2018

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Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

21 January 2018

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Adaptive immunity in rheumatoid arthritis: anticitrulline and other antibodies in the pathogenesis of rheumatoid arthritis

21 January 2018

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Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

21 January 2018

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NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

21 January 2018

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Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

21 January 2018

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Stromal cells in chronic inflammation and tertiary lymphoid organ formation

21 January 2018

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Positive anti-cyclic citrullinated proteins and rheumatoid factor during active lung tuberculosis

21 January 2018

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The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment

21 January 2018

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Poncet's disease with high titers of rheumatoid factor and anti-citrullinated peptide antibodies mimicking rheumatoid arthritis

21 January 2018

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Anti-citrullinated peptide antibodies in Sudanese patients with Leishmania donovani infection exhibit reactivity not dependent on citrullination

21 January 2018

1 reference

Toll-like receptors and B cells: functions and mechanisms

21 January 2018

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

Rheumatoid factors: good or bad for you?

21 January 2018

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Rheumatoid factor revisited

21 January 2018

1 reference

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation.

21 January 2018

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Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells

21 January 2018

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The B Cell-Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell-Dependent Bone Loss in Experimental Murine Periodontitis

21 January 2018

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Circulating Human CD27-IgA+ Memory B Cells Recognize Bacteria with Polyreactive Igs

21 January 2018

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Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy

21 January 2018

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CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.

21 January 2018

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Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

21 January 2018

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Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis

21 January 2018

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A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

21 January 2018

1 reference

21 January 2018

MHC class II tetramers

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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

21 January 2018

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Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important

21 January 2018

1 reference

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

21 January 2018

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Interactions between amino acid-defined major histocompatibility complex class II variants and smoking in seropositive rheumatoid arthritis

21 January 2018

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Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

21 January 2018

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Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

21 January 2018

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Barcode-enabled sequencing of plasmablast antibody repertoires in rheumatoid arthritis.

21 January 2018

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The cellular composition of lymph nodes in the earliest phase of inflammatory arthritis

21 January 2018

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Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis

21 January 2018

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Discriminating gene expression profiles of memory B cell subpopulations.

21 January 2018

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Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis

21 January 2018

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Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis

21 January 2018

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Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice

21 January 2018

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Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

21 January 2018

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Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

21 January 2018

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Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation

21 January 2018

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Autoimmunity in rheumatoid arthritis: citrulline immunity and beyond

21 January 2018

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Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

21 January 2018

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The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

21 January 2018

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Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/IMR.12379

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5 September 2017

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