(Q38689249)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Hydrophobic Patch of Ubiquitin is Important for its Optimal Activation by Ubiquitin Activating Enzyme E1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Rajesh K Singh

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Yaniv Kazansky

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Donald Wathieu

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

language of work or name

English

0 references

publication date

20 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

7852-7860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

cites work

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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

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Phosphorylated ubiquitin chain is the genuine Parkin receptor.

23 June 2018

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Polyhydroxylated [60]fullerene binds specifically to functional recognition sites on a monomeric and a dimeric ubiquitin

23 June 2018

1 reference

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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

23 June 2018

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Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains

23 June 2018

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SCFs in the new millennium

23 June 2018

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Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer

23 June 2018

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Analyses of the effects of all ubiquitin point mutants on yeast growth rate

23 June 2018

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Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system

23 June 2018

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

23 June 2018

1 reference

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Ubiquitination in signaling to and activation of IKK.

23 June 2018

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Ubiquitin and proteasomes in transcription

23 June 2018

1 reference

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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The NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cells

23 June 2018

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The E2-25K ubiquitin-associated (UBA) domain aids in polyubiquitin chain synthesis and linkage specificity

23 June 2018

1 reference

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A natural product-like inhibitor of NEDD8-activating enzyme

23 June 2018

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The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

23 June 2018

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23 June 2018

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Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets

23 June 2018

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Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity

23 June 2018

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Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.

23 June 2018

1 reference

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

23 June 2018

1 reference

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Active site remodelling accompanies thioester bond formation in the SUMO E1

23 June 2018

1 reference

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

23 June 2018

1 reference

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UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex

23 June 2018

1 reference

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Direct activation of protein kinases by unanchored polyubiquitin chains

23 June 2018

1 reference

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The ubiquitin proteasome system in neuropathology

23 June 2018

1 reference

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Degradation of activated protein kinases by ubiquitination

23 June 2018

1 reference

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

A role for ubiquitin in the spliceosome assembly pathway

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Polyubiquitin chains: polymeric protein signals

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

A proteomics approach to understanding protein ubiquitination

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Structural properties of polyubiquitin chains in solution

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Mechanisms underlying ubiquitination

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

A 25-kilodalton ubiquitin carrier protein (E2) catalyzes multi-ubiquitin chain synthesis via lysine 48 of ubiquitin

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Phosphorylation of ubiquitin at Ser65 affects its polymerization, targets, and proteome-wide turnover

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Nonenzymatic rubylation and ubiquitination of proteins for structural and functional studies

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Analysis of the biochemical role of Lys-11 in polyubiquitin chain formation using quantitative mass spectrometry.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Interdomain mobility in di-ubiquitin revealed by NMR.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

In vitro assembly and recognition of Lys-63 polyubiquitin chains

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573600

Dissecting roles of ubiquitination in the p53 pathway

31 August 2018

1 reference

12 December 2020

Ubiquitin adenylate: structure and role in ubiquitin activation

1 reference

12 December 2020

Site-directed mutagenesis of ubiquitin. Differential roles for arginine in the interaction with ubiquitin-activating enzyme

1 reference

12 December 2020

Ubiquitin carboxyl-terminal peptides. Substrates for ubiquitin activating enzyme

1 reference

12 December 2020

Steady-state kinetic analysis of human ubiquitin-activating enzyme (E1) using a fluorescently labeled ubiquitin substrate

1 reference

12 December 2020

10.1021/ACS.ANALCHEM.6B04194

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28686836%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

28686836

1 reference