(Q39607125)

13 September 2017

title

A natural product-like inhibitor of NEDD8-activating enzyme (English)

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13 September 2017

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6

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Dik-Lung Ma

8

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Ruben Abagyan

4

object named as

Ruben Abagyan

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Chung-Hang Leung

1

object named as

Chung-Hang Leung

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13 September 2017

Daniel Shiu-Hin Chan

2

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13 September 2017

Hui Yang

3

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13 September 2017

Simon Ming-Yuen Lee

5

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13 September 2017

Wang-Fun Fong

7

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13 September 2017

language of work or name

English

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publication date

14 January 2011

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13 September 2017

published in

Chemical Communications

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13 September 2017

volume

47

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13 September 2017

issue

9

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13 September 2017

page(s)

2511-2513

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Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer.

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Development of the proteasome inhibitor Velcade (Bortezomib).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Nedd8 on cullin: building an expressway to protein destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Integration of virtual and high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Virtual screening of chemical libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Structure-based discovery of natural-product-like TNF-α inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Natural products--a simple model to explain chemical diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Drug discovery and natural products: end of an era or an endless frontier?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Synthesis of biologically relevant biflavanoids--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Biflavonoids inhibit the production of aflatoxin by Aspergillus flavus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

Biflavonoids as novel antituberculosis agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

An unusual C6–C6″ linked flavonoid from Miconia cabucu (Melastomataceae)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC04927A

21 January 2018

Identifiers

DOI

10.1039/C0CC04927A

1 reference

13 September 2017

1 reference