(Q38706796)

5 September 2017

title

Modulating the therapeutic response of tumours to dietary serine and glycine starvation (English)

1 reference

Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation

5 September 2017

corrigendum / erratum

0 references

author

Oliver D K Maddocks

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Dimitris Athineos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Pearl Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

David M. Gay

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Owen J Sansom

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Karen Blyth

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

17

Karen H Vousden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Eric C Cheung

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Tong Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Niels J F van den Broek

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Gillian M Mackay

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Christiaan F Labuschagne

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Flore Kruiswijk

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Julianna Blagih

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

David F Vincent

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Kirsteen J Campbell

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Fatih Ceteci

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

1 April 2017

1 reference

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

544

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

7650

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

372-376

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature22056

7 June 2020

exact match

0 references

cites work

Serine, glycine and one-carbon units: cancer metabolism in full circle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Genetic selection for enhanced serine metabolism in cancer development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine deprivation enhances antineoplastic activity of biguanides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Repositioning metformin for cancer prevention and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Dose translation from animal to human studies revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Effect of metformin on oxidative stress, nitrosative stress and inflammatory biomarkers in type 2 diabetes patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Effects of metformin on markers of oxidative stress and antioxidant reserve in patients with newly diagnosed type 2 diabetes: a randomized clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Modulation of intracellular ROS levels by TIGAR controls autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

NRF2 regulates serine biosynthesis in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Application of Holistic Liquid Chromatography-High Resolution Mass Spectrometry Based Urinary Metabolomics for Prostate Cancer Detection and Biomarker Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Serine Is an Essential Metabolite for Effector T Cell Expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056

Enzymes of serine metabolism in normal and neoplastic rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE22056