(Q38706796)

5 September 2017

Modulating the therapeutic response of tumours to dietary serine and glycine starvation (English)

1 reference

Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation

5 September 2017

corrigendum / erratum

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author

Oliver D K Maddocks

1

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7 June 2020

Dimitris Athineos

2

1 reference

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7 June 2020

Pearl Lee

4

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7 June 2020

David M. Gay

9

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7 June 2020

Owen J Sansom

15

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7 June 2020

Karen Blyth

16

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7 June 2020

17

Karen H Vousden

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7 June 2020

author name string

Eric C Cheung

3

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7 June 2020

Tong Zhang

5

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7 June 2020

Niels J F van den Broek

6

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7 June 2020

Gillian M Mackay

7

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7 June 2020

Christiaan F Labuschagne

8

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7 June 2020

Flore Kruiswijk

10

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7 June 2020

Julianna Blagih

11

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7 June 2020

David F Vincent

12

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7 June 2020

Kirsteen J Campbell

13

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7 June 2020

Fatih Ceteci

14

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7 June 2020

language of work or name

English

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publication date

1 April 2017

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5 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28425994%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

544

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7 June 2020

issue

7650

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7 June 2020

page(s)

372-376

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https://scigraph.springernature.com/pub.10.1038/nature22056

7 June 2020

exact match

0 references

cites work

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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

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Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

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Serine deprivation enhances antineoplastic activity of biguanides.

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2

21 January 2018

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Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

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Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

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