(Q38706852)

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Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling

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Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

G protein-coupled receptor

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2

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

author name string

Ayush Kishore

1

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Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

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publication date

19 April 2017

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Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

292

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Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

23

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

9711-9720

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

Versatile Signaling Activity of Adhesion GPCRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56/ADGRG1 Activation Promotes Melanoma Cell Migration via NTF Dissociation and CTF-Mediated Gα12/13/RhoA Signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The adhesion GPCR latrophilin/CIRL shapes mechanosensation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Bilateral frontoparietal polymicrogyria: a novel GPR56 mutation and an unusual phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Chaperoning G protein-coupled receptors: from cell biology to therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

β-arrestins and G protein-coupled receptor trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle development in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56 functions together with α3β1 integrin in regulating cerebral cortical development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Matching structure with function: the GAIN domain of adhesion-GPCR and PKD1-like proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Sticky signaling--adhesion class G protein-coupled receptors take the stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Comparative phosphoproteomic analysis of neonatal and adult murine brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Specific expression of GPR56 by human cytotoxic lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56 Regulates VEGF production and angiogenesis during melanoma progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56-regulated granule cell adhesion is essential for rostral cerebellar development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Disease-associated mutations affect GPR56 protein trafficking and cell surface expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

G protein-coupled receptor-dependent development of human frontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

SK&F 96365, a novel inhibitor of receptor-mediated calcium entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

23 June 2018

Adhesion G Protein-Coupled Receptor G1 (ADGRG1/GPR56) and Pancreatic β-Cell Function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

31 August 2018

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465494

31 August 2018

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/28424266

12 December 2020

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Identifiers

10.1074/JBC.M117.780551

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 June 2018

http://europepmc.org/abstract/PMC/5465494

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