(Q38715538)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

review article

1 reference

title

The rationale for targeting TGF-β in chronic liver diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

main subject

chronic liver disease

0 references

author

Gianluigi Giannelli

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Wolfgang Mikulits

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Isabel Fabregat

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Stefano Leporatti

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Aránzazu Sánchez

12

1 reference

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6 March 2020

author name string

Steven Dooley

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Aristidis Moustakas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Peter ten Dijke

6

1 reference

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6 March 2020

Piero Portincasa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Peter Winter

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Richard Janssen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Blanca Herrera

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

publication date

12 March 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Clinical Investigation

6 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

349-361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26823073%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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21 January 2018

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21 January 2018

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Structural determinants of Smad function in TGF-β signaling.

21 January 2018

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TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

21 January 2018

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TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.

21 January 2018

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Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.

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USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

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RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation

21 January 2018

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Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

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What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis

21 January 2018

1 reference

The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo

21 January 2018

1 reference

The role of Smad3 in mediating mouse hepatic stellate cell activation

21 January 2018

1 reference

Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization

21 January 2018

1 reference

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response

21 January 2018

1 reference

Inactivation of the deubiquitinase CYLD in hepatocytes causes apoptosis, inflammation, fibrosis, and cancer.

21 January 2018

1 reference

Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo

21 January 2018

1 reference

The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.

21 January 2018

1 reference

Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

21 January 2018

1 reference

TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells

21 January 2018

1 reference

NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.

21 January 2018

1 reference

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.

21 January 2018

1 reference

Anti-TGF-beta strategies for the treatment of chronic liver disease

21 January 2018

1 reference

Cytokines and lipid peroxidation in alcoholics with chronic hepatitis C virus infection.

21 January 2018

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Alcohol and hepatitis C virus core protein additively increase lipid peroxidation and synergistically trigger hepatic cytokine expression in a transgenic mouse model

21 January 2018

1 reference

TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I.

21 January 2018

1 reference

Alcohol Activates TGF-Beta but Inhibits BMP Receptor-Mediated Smad Signaling and Smad4 Binding to Hepcidin Promoter in the Liver

21 January 2018

1 reference

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

21 January 2018

1 reference

Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells

21 January 2018

1 reference

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

Molecular mechanisms of epithelial-mesenchymal transition

21 January 2018

1 reference

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

21 January 2018

1 reference

The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

TGF-β in epithelial to mesenchymal transition and metastasis of liver carcinoma.

21 January 2018

1 reference

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.

21 January 2018

1 reference

Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

21 January 2018

1 reference

Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis.

21 January 2018

1 reference

PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression.

21 January 2018

1 reference

PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.

21 January 2018

1 reference

La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition

21 January 2018

1 reference

Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion

21 January 2018

1 reference

Epithelial-mesenchymal transition in hepatocellular carcinoma.

21 January 2018

1 reference

Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma

21 January 2018

1 reference

Hepatic stellate cells stimulate HCC cell migration via laminin-5 production.

21 January 2018

1 reference

Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins.

21 January 2018

1 reference

Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

21 January 2018

1 reference

Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma

21 January 2018

1 reference

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

21 January 2018

1 reference

Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation

21 January 2018

1 reference

EGFR and VEGFR as potential target for biological therapies in HCC cells.

21 January 2018

1 reference

When good transforming growth factor-β turns bad in hepatocellular carcinoma: Axl takes the stage.

21 January 2018

1 reference

Axl activates autocrine transforming growth factor-β signaling in hepatocellular carcinoma

21 January 2018

1 reference

Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition

21 January 2018

1 reference

A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration

21 January 2018

1 reference

Elevated urinary transforming growth factor-beta1 level as a tumour marker and predictor of poor survival in cirrhotic hepatocellular carcinoma

21 January 2018

1 reference

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

21 January 2018

1 reference

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

21 January 2018

1 reference

Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study.

21 January 2018

1 reference

Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

21 January 2018

1 reference

The functional impairment of HCC-infiltrating γδ T cells, partially mediated by regulatory T cells in a TGFβ- and IL-10-dependent manner

21 January 2018

1 reference

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21 January 2018

1 reference

Immune response and survival of refractory cancer patients who received TGF-β2 antisense/GM-CSF gene modified autologous tumor cell (TAG) vaccine

21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer

21 January 2018

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21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

Polyelectrolyte capsules as carriers for growth factor inhibitor delivery to hepatocellular carcinoma

21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference