(Q38718016)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Neil Halliday

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Waseem Qasim

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Sophie Hambleton

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Siobhan O Burns

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

David M Sansom

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

14

Olaf Neth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

9

Austen Worth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Tie Zheng Hou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Nisha Verma

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Jennifer Wanders

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Blagoje Soskic

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Daniel Janman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Behzad Rowshanravan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Helen Baxendale

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Hans Stauss

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Suranjith Seneviratne

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Peter Olbrich

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Peter D Arkwright

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Lucy S K Walker

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

language of work or name

English

0 references

publication date

3 February 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

1458-1468

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

CHAI and LATAIE: new genetic diseases of CTLA-4 checkpoint insufficiency

1 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Genetic Diagnosis Using Whole Exome Sequencing in Common Variable Immunodeficiency

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Genes associated with common variable immunodeficiency: one diagnosis to rule them all?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

CD28 Costimulation: From Mechanism to Therapy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Confusing signals: recent progress in CTLA-4 biology

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

A transendocytosis perspective on the CD28/CTLA-4 pathway

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Treg and CTLA-4: two intertwining pathways to immune tolerance

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Update in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

CTLA-4 control over Foxp3+ regulatory T cell function

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Epigenetic control of the foxp3 locus in regulatory T cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Lack of intrinsic CTLA-4 expression has minimal effect on regulation of antiviral T-cell immunity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

IMMUNOLOGY. Moving CTLA-4 from the trash to recycling.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Clinical picture and treatment of 2212 patients with common variable immunodeficiency

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438243

Autoimmune lymphoproliferative syndrome-like disease in patients with LRBA mutation

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28159733

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2016-10-745174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28159733%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference