(Q38736125)

6 September 2017

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage (English)

1 reference

6 September 2017

0 references

1 reference

1 reference

4

1 reference

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4 June 2020

Ashish Rajput

7

1 reference

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4 June 2020

Ana Cristina Rego

11

1 reference

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4 June 2020

Tiago Fleming Outeiro

14

1 reference

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4 June 2020

author name string

Isabel Paiva

1

1 reference

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4 June 2020

Raquel Pinho

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28369321%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Maria Angeliki Pavlou

3

1 reference

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4 June 2020

Pauline Wales

5

1 reference

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4 June 2020

Anna-Lena Schütz

6

1 reference

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4 June 2020

Éva M Szego

8

1 reference

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4 June 2020

Cemil Kerimoglu

9

1 reference

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4 June 2020

Ellen Gerhardt

10

1 reference

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4 June 2020

André Fischer

12

1 reference

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4 June 2020

Stefan Bonn

13

1 reference

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4 June 2020

publication date

24 March 2017

1 reference

6 September 2017

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28369321%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

26

1 reference

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4 June 2020

issue

12

1 reference

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4 June 2020

page(s)

2231-2246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28369321%20AND%20SRC:MED&resulttype=core&format=json

Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa

4 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Non-motor symptoms of Parkinson's disease: diagnosis and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Transcriptional dysregulation in a transgenic model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Wild-type and mutant alpha-synuclein induce a multi-component gene expression profile consistent with shared pathophysiology in different transgenic mouse models of PD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Interference of alpha-synuclein with cAMP/PKA-dependent CREB signaling for tyrosine hydroxylase gene expression in SK-N-BE(2)C cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Nuclear localization of alpha-synuclein and its interaction with histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

HDAC inhibitors: roles of DNA damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Anti-parkinsonian effects of Nurr1 activator in ubiquitin-proteasome system impairment induced animal model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

α-Synuclein overexpression represses 14-3-3θ transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Parametric mapping of [18F]FPCIT binding in early stage Parkinson's disease: a PET study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Transcriptional abnormalities in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Transcriptional regulation and its misregulation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Cell cycle aberrations by alpha-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

DNA damage and its links to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

DNA repair, mitochondria, and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

BRCA1 and p53 tumor suppressor molecules in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

The associations between Parkinson's disease and cancer: the plot thickens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Fe(II)‐induced DNA damage in α‐synuclein‐transfected human dopaminergic BE(2)‐M17 neuroblastoma cells: detection by the Comet assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mitochondrial Dysfunction in Parkinson's Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mitochondrial α-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mitochondrial association of alpha-synuclein causes oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Biophysics of α-synuclein membrane interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

The role of mitochondria in apoptosis*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Real-Time Quantitative Reverse Transcriptase-Polymerase Chain Reaction as a Method for Determining Lentiviral Vector Titers and Measuring Transgene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX114

21 January 2018

Identifiers

DOI

10.1093/HMG/DDX114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28369321%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference