(Q36234694)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Leslie Crews

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Beate Winner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

11

Eliezer Masliah

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Brian Spencer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Pruthul Pathel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Dinorah Morvinski-Friedmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kori Kosberg

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Scott Roberts

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Christina Patrick

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Juergen Winkler

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

25 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

31691-31702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

Not(ch) just development: Notch signalling in the adult brain

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Protein-DNA Interaction at the Origin of Neurological Diseases: A Hypothesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

DNA induced folding/fibrillation of alpha-synuclein: new insights in Parkinson's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Redefining the p53 response element

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

1 October 2017

It's T-ALL about Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Olfactory deficits in mice overexpressing human wildtype alpha-synuclein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Development of neural stem cell in the adult brain

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Regulation of Notch1 gene expression by p53 in epithelial cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch signalling: a simple pathway becomes complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch signalling in vertebrate neural development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Maintaining appearances--the role of p53 in adult neurogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Challenges and complexities of alpha-synuclein toxicity: new postulates in unfolding the mystery associated with Parkinson's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Parkinson's disease: mechanisms and models

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

SiteSeer: Visualisation and analysis of transcription factor binding sites in nucleotide sequences

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Functional neurogenesis in the adult hippocampus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

1 October 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Running enhances neurogenesis, learning, and long-term potentiation in mice

1 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

1 October 2017

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Alpha-synuclein in Lewy bodies

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Definition of a consensus binding site for p53

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Turning neurogenesis up a Notch

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Changes in the expression of Hes5 and Mash1 mRNA in the adult rat dentate gyrus after transient forebrain ischemia

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Differential regulation of basic helix-loop-helix mRNAs in the dentate gyrus following status epilepticus

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Clonal cell lines from the rat central nervous system.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442504

Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.

29 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Multipotent progenitor cells in the adult dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Production and purification of lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

p53 suppresses the self-renewal of adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Human Wild-Type α-Synuclein Impairs Neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.354522

Crosstalk of Notch with p53 and p63 in cancer growth control

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22833673

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective hippocampal neuron loss in dementia with Lewy bodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22833673

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.354522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22833673%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

22833673

1 reference