(Q38778206)

19 July 2018

title

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers (English)

1 reference

19 July 2018

main subject

pulmonary hypertension

1 reference

19

Joseph C Wu

1 reference

19 July 2018

Jaecheol Lee

10

object named as

Jaecheol Lee

1 reference

19 July 2018

author name string

Mingxia Gu

1

1 reference

19 July 2018

Ning-Yi Shao

2

1 reference

19 July 2018

Silin Sa

3

1 reference

19 July 2018

Dan Li

4

1 reference

19 July 2018

Vittavat Termglinchan

5

1 reference

19 July 2018

Mohamed Ameen

6

1 reference

19 July 2018

Ioannis Karakikes

7

1 reference

19 July 2018

Gustavo Sosa

8

1 reference

19 July 2018

Fabian Grubert

9

1 reference

19 July 2018

Aiqin Cao

11

1 reference

19 July 2018

Shalina Taylor

12

1 reference

19 July 2018

Yu Ma

13

1 reference

19 July 2018

Zhixin Zhao

14

1 reference

19 July 2018

James Chappell

15

1 reference

19 July 2018

Rizwan Hamid

16

1 reference

19 July 2018

Eric D Austin

17

1 reference

19 July 2018

Joseph D Gold

18

1 reference

19 July 2018

Michael P Snyder

20

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19 July 2018

Marlene Rabinovitch

21

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19 July 2018

language of work or name

English

0 references

publication date

22 December 2016

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19 July 2018

published in

Cell Stem Cell

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19 July 2018

volume

20

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19 July 2018

issue

4

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19 July 2018

page(s)

490-504.e5

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19 July 2018

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug

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1 reference

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Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension.

27 July 2018

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High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s)

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Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.

27 July 2018

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27 July 2018

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27 July 2018

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Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

27 July 2018

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Gremlin plays a key role in the pathogenesis of pulmonary hypertension

27 July 2018

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27 July 2018

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Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

27 July 2018

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Nitric oxide-induced collagen IV expression and angiogenesis: FAK or fiction? Focus on "Collagen IV contributes to nitric oxide-induced angiogenesis of lung endothelial cells".

27 July 2018

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Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

27 July 2018

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Calcium-activated potassium channels and endothelial dysfunction: therapeutic options?

27 July 2018

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Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.

27 July 2018

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Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

27 July 2018

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Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta

27 July 2018

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In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

27 July 2018

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EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown

27 July 2018

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Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension

27 July 2018

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Low density lipoprotein receptor-related protein-1 promotes beta1 integrin maturation and transport to the cell surface

27 July 2018

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Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia

27 July 2018

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Selective blockade of endothelial Ca2+-activated small- and intermediate-conductance K+-channels suppresses EDHF-mediated vasodilation

27 July 2018

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Endothelium-dependent relaxation competes with alpha 1- and alpha 2-adrenergic constriction in the canine epicardial coronary microcirculation

27 July 2018

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Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

27 July 2018

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Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor

27 July 2018

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RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.

27 July 2018

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BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension

31 August 2018

1 reference

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Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.

31 August 2018

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Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency

31 August 2018

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Comparison of the transcriptional landscapes between human and mouse tissues

31 August 2018

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Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism

31 August 2018

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Death receptor 3 mediates TNFSF15- and TNFα-induced endothelial cell apoptosis

31 August 2018

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Double disruption of α2A- and α2C-adrenoceptors induces endothelial dysfunction in mouse small arteries: role of nitric oxide synthase uncoupling.

31 August 2018

1 reference

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Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats

31 August 2018

1 reference

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A novel channelopathy in pulmonary arterial hypertension

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Endothelial dysfunction in pulmonary hypertension

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Angiogenesis and pulmonary hypertension: a unique process in a unique disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Vascular adrenoceptors: an update.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Wounding activates p38 map kinase and activation transcription factor 3 in leading keratinocytes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500296

Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28017794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEM.2016.08.019

1 reference

19 July 2018

PMC publication ID

5500296

1 reference

19 July 2018

PubMed publication ID

28017794

1 reference

19 July 2018