(Q38786643)

6 September 2017

title

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI). (English)

1 reference

6 September 2017

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Alberto Munoz

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

J. Ignacio Casal

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

I García-Palmero

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

S Torres

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

R A Bartolomé

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

A Peláez-García

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

M Lopez-Lucendo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

C Peña

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

B Escudero-Paniagua

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

14 March 2016

1 reference

6 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

5224-5236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

Regulatory networks defining EMT during cancer initiation and progression

1 June 2020

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Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients

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Twist1-induced invadopodia formation promotes tumor metastasis.

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TWIST1 is expressed in colorectal carcinomas and predicts patient survival

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Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

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Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes.

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TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer.

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Tensional homeostasis and the malignant phenotype

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Assembly of Fibronectin Extracellular Matrix

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Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

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A tense situation: forcing tumour progression

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Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.

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TGF-beta-induced epithelial to mesenchymal transition

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Mechanisms of the epithelial-mesenchymal transition by TGF-beta

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Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion

21 January 2018

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Quantitative secretome analysis reveals that COL6A1 is a metastasis-associated protein using stacking gel-aided purification combined with iTRAQ labeling

21 January 2018

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High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes

21 January 2018

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Isoform-specific upregulation of palladin in human and murine pancreas tumors

21 January 2018

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Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma

21 January 2018

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Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients

21 January 2018

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Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

21 January 2018

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Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

21 January 2018

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Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

21 January 2018

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Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts.

21 January 2018

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Palladin is a dynamic actin-associated protein in podocytes

21 January 2018

1 reference

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Palladin regulates cell and extracellular matrix interaction through maintaining normal actin cytoskeleton architecture and stabilizing beta1-integrin.

21 January 2018

1 reference

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The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies

21 January 2018

1 reference

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Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

21 January 2018

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Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironment

21 January 2018

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The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration

21 January 2018

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Akt2 regulates expression of the actin-bundling protein palladin

21 January 2018

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Regulation of cancer cell survival, migration, and invasion by Twist: AKT2 comes to interplay

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Palladin expression is a conserved characteristic of the desmoplastic tumor microenvironment and contributes to altered gene expression

21 January 2018

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The actin associated protein palladin is important for the early smooth muscle cell differentiation

21 January 2018

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Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)

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LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.

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Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer

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IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.

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Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis.

21 January 2018

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Twist, an independent prognostic marker for predicting distant metastasis and survival rates of esophageal squamous cell carcinoma patients

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Twist1 is a key regulator of cancer-associated fibroblasts.

31 March 2020

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High expression of Twist is associated with tumor aggressiveness and poor prognosis in patients with renal cell carcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26973246

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of Twist in head and neck carcinoma with lymph node metastasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26973246

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

1014282203

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973246%20AND%20SRC:MED&resulttype=core&format=json