(Q34145927)

31 July 2017

title

Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion (English)

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31 July 2017

1 reference

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Teresa A Brentnall

1

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31 July 2017

Lisa A Lai

2

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31 July 2017

Joshua Coleman

3

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31 July 2017

Mary P Bronner

4

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31 July 2017

Sheng Pan

5

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31 July 2017

Ru Chen

6

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31 July 2017

language of work or name

English

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publication date

23 January 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

1

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31 July 2017

page(s)

e30219

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

23 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3264580/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

5 July 2018

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Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer

5 July 2018

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5 July 2018

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The actin associated protein palladin is important for the early smooth muscle cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

5 July 2018

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Novel invadopodia components revealed by differential proteomic analysis.

5 July 2018

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The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration

5 July 2018

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Activation of fibroblasts in cancer stroma

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Isoform-specific upregulation of palladin in human and murine pancreas tumors

5 July 2018

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Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia

5 July 2018

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Ras activity levels control the development of pancreatic diseases.

5 July 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

5 July 2018

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Absence of deleterious palladin mutations in patients with familial pancreatic cancer.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

5 July 2018

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Stromal myofibroblasts are drivers of invasive cancer growth

5 July 2018

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Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

5 July 2018

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No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Tri-nucleotide receptors play a critical role in epithelial cell wound repair.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

The role of palladin in actin organization and cell motility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Assembly and biological role of podosomes and invadopodia

5 July 2018

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Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

5 July 2018

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Molecular pathogenesis of pancreatic cancer: advances and challenges

5 July 2018

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Molecular genetics of pancreatic intraepithelial neoplasia

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Palladin mutation causes familial pancreatic cancer: absence in European families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Reprogramming metastatic tumour cells with embryonic microenvironments

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Stromal biology of pancreatic cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Cancer metastasis: building a framework

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

5 July 2018

Fibroblasts in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Identification of palladin isoforms and characterization of an isoform-specific interaction between Lasp-1 and palladin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Catalytically inactive human cathepsin D triggers fibroblast invasive growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Stromal fibroblasts in cancer initiation and progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Reconstruction of functionally normal and malignant human breast tissues in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Role of tissue stroma in cancer cell invasion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Frequent expression of smooth muscle markers in malignant fibrous histiocytoma of bone

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Malignant transformation in a nontumorigenic human prostatic epithelial cell line.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Reactive stroma in prostate cancer progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

A role for the cytoskeleton-associated protein palladin in neurite outgrowth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Invasion-specific genes in malignancy: serial analysis of gene expression comparisons of primary and passaged cancers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Invadopodia: unique methods for measurement of extracellular matrix degradation in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Characterization of palladin, a novel protein localized to stress fibers and cell adhesions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Tissue microarrays for high-throughput molecular profiling of tumor specimens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Palladin regulates cell and extracellular matrix interaction through maintaining normal actin cytoskeleton architecture and stabilizing beta1-integrin.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030219

Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030219

Transforming growth factor-beta 1 specifically induce proteins involved in the myofibroblast contractile apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030219

The stroma as a crucial target in rat mammary gland carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0030219

Methods for pseudopodia purification and proteomic analysis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264580

Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families

28 October 2018

1 reference

12 December 2020

Age-dependent induction of hepatic tumor regression by the tissue microenvironment after transplantation of neoplastically transformed rat liver epithelial cells into the liver

1 reference

12 December 2020

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

1 reference

12 December 2020

Actinin-4 expression in ovarian cancer: a novel prognostic indicator independent of clinical stage and histological type

1 reference

12 December 2020

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12 December 2020

Checking out the neighbourhood

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0030219

Identifiers

DOI

1 reference

31 July 2017

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31 July 2017

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