(Q38787449)

English

Phase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells

scientific article published on 07 March 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 September 2017

Phase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells (English)

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Europe PubMed Central

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6 September 2017

phase I clinical trial

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author name string

Fengtao You

1

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6 September 2017

Licui Jiang

2

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6 September 2017

Bozhen Zhang

3

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6 September 2017

Qiang Lu

4

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6 September 2017

Qiao Zhou

5

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6 September 2017

Xiaoyang Liao

6

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6 September 2017

Hong Wu

7

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6 September 2017

Kaiqi Du

8

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6 September 2017

Youcai Zhu

9

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6 September 2017

Huimin Meng

10

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6 September 2017

Zhishu Gong

11

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6 September 2017

Yunhui Zong

12

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6 September 2017

Lei Huang

13

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6 September 2017

Man Lu

14

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6 September 2017

Jirong Tang

15

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6 September 2017

Yafen Li

16

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6 September 2017

Xiaochen Zhai

17

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6 September 2017

Xiangling Wang

18

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6 September 2017

Sisi Ye

19

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6 September 2017

Dan Chen

20

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6 September 2017

Lei Yuan

21

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6 September 2017

Lin Qi

22

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6 September 2017

Lin Yang

23

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6 September 2017

publication date

7 March 2016

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6 September 2017

Science in China. Series C: Life Sciences

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6 September 2017

59

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6 September 2017

4

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6 September 2017

386-397

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6 September 2017

https://scigraph.springernature.com/pub.10.1007/s11427-016-5024-7

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The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.

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Structure and biology of a carcinoma-associated mucin, MUC1.

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Designing a recombinant chimeric construct contain MUC1 and HER2 extracellular domain for prediagnostic breast cancer.

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Identification of TIA-1+ and granzyme B+ cytotoxic T cells in lichen sclerosus et atrophicus

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

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Chimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer

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Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells

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The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers.

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Chimeric antigen receptors with mutated IgG4 Fc spacer avoid fc receptor binding and improve T cell persistence and antitumor efficacy

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MUC1 immunotherapy is here to stay

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CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation

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Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity

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T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness

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Chemotactic antiviral cytokines promote infectious apical entry of human adenovirus into polarized epithelial cells.

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Potential for novel MUC1 glycopeptide-specific antibody in passive cancer immunotherapy

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CAR mechanics: driving T cells into the MUC of cancer

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Chimeric antigen receptor T cells for sustained remissions in leukemia

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10.1007/S11427-016-5024-7

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Europe PubMed Central

PubMed publication ID

6 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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