(Q38795629)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26855149%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma (English)

1 reference

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7 March 2020

1 reference

1

1 reference

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7 March 2020

Gonzalo Gómez-López

2

1 reference

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7 March 2020

Mattia Falcone

3

1 reference

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7 March 2020

August Vidal

4

1 reference

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7 March 2020

Ernest Nadal

5

1 reference

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7 March 2020

Montse Sanchez-Cespedes

9

1 reference

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7 March 2020

Ke Ding

12

1 reference

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7 March 2020

Manuel Serrano

14

1 reference

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7 March 2020

author name string

Nicola Crosetto

6

1 reference

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7 March 2020

Rafael B Blasco

7

1 reference

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7 March 2020

Pablo J Fernández-Marcos

8

1 reference

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7 March 2020

Xiaomei Ren

10

1 reference

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7 March 2020

Zhen Wang

11

1 reference

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7 March 2020

Manuel Hidalgo

13

1 reference

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7 March 2020

Alberto Villanueva

15

1 reference

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7 March 2020

David Santamaría

16

1 reference

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7 March 2020

Mariano Barbacid

17

1 reference

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7 March 2020

language of work or name

English

0 references

publication date

8 February 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26855149%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26855149%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

22

1 reference

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7 March 2020

issue

3

1 reference

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7 March 2020

page(s)

270-277

1 reference

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https://scigraph.springernature.com/pub.10.1038/nm.4041

7 March 2020

exact match

0 references

cites work

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Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: a systematic review with meta-analysis

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The evolution of the unstable cancer genome

21 January 2018

1 reference

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

21 January 2018

1 reference

Discoidin domain receptor tyrosine kinases: new players in cancer progression

21 January 2018

1 reference

Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis.

21 January 2018

1 reference

Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung cancer and promotes cell invasion via epithelial-to-mesenchymal transition

21 January 2018

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

21 January 2018

1 reference

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

21 January 2018

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Multiple tyrosine protein kinases in rat hippocampal neurons: isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain

21 January 2018

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Discoidin domain receptor functions in physiological and pathological conditions

21 January 2018

1 reference

Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development

21 January 2018

1 reference

Discoidin domain receptor 1 is a major mediator of inflammation and fibrosis in obstructive nephropathy

21 January 2018

1 reference

Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors

21 January 2018

1 reference

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation

21 January 2018

1 reference

Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK

21 January 2018

1 reference

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53

21 January 2018

1 reference

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

21 January 2018

1 reference

Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

21 January 2018

1 reference

Alterations of the Notch pathway in lung cancer.

21 January 2018

1 reference

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

21 January 2018

1 reference

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

21 January 2018

1 reference

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

21 January 2018

1 reference

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

1 reference

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

21 January 2018

1 reference

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

21 January 2018

1 reference

Identifying direct Notch transcriptional targets using the GSI-washout assay

21 January 2018

1 reference

Tumour heterogeneity and cancer cell plasticity

21 January 2018

1 reference

Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma.

21 January 2018

1 reference

Alveolar progenitor and stem cells in lung development, renewal and cancer.

21 January 2018

1 reference

Translational value of mouse models in oncology drug development

21 January 2018

1 reference

Preclinical mouse cancer models: a maze of opportunities and challenges

21 January 2018

1 reference

Phase II study of dasatinib in patients with advanced non-small-cell lung cancer

21 January 2018

1 reference

c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma

21 January 2018

1 reference

C-Raf is required for the initiation of lung cancer by K-Ras(G12D).

21 January 2018

1 reference

Discoidin domain receptor 1 expression in activated T cells is regulated by the ERK MAP kinase signaling pathway.

21 January 2018

1 reference

Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells.

21 January 2018

1 reference

Therapeutic modulation of Notch signalling--are we there yet?

21 January 2018

1 reference

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts

21 January 2018

1 reference

Fast and accurate long-read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

21 January 2018

1 reference

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

21 January 2018

1 reference

Use of within-array replicate spots for assessing differential expression in microarray experiments.

21 January 2018

1 reference

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

21 January 2018

1 reference

A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

21 January 2018

1 reference

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

21 January 2018

1 reference

12 December 2020

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium

1 reference

12 December 2020

Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas.

1 reference

12 December 2020

Clinically accurate orthotopic mouse models of cancer

1 reference

12 December 2020

Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas

1 reference

12 December 2020