(Q38823264)

6 September 2017

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title

Vaccine platforms to control Lassa fever (English)

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6 September 2017

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2

Peter Pushko

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6 September 2017

1

Igor S Lukashevich

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6 September 2017

publication date

3 May 2016

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Expert Review of Vaccines

6 September 2017

published in

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6 September 2017

volume

15

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6 September 2017

issue

9

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6 September 2017

page(s)

1135-1150

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The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

6 September 2017

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Genetic diversity among Lassa virus strains

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Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus

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Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections

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Geographic distribution and genetic characterization of Lassa virus in sub-Saharan Mali

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Lassa fever in West Africa: evidence for an expanded region of endemicity

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Strain-specific antibody response to Lassa virus in the local population of west Africa

21 January 2018

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Hemorrhagic fever viruses as biological weapons: medical and public health management

21 January 2018

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The impact of human conflict on the genetics of Mastomys natalensis and Lassa virus in West Africa

21 January 2018

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A prospective study of the epidemiology and ecology of Lassa fever

21 January 2018

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New opportunities for field research on the pathogenesis and treatment of Lassa fever

21 January 2018

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Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever

21 January 2018

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Genome-wide detection and characterization of positive selection in human populations

21 January 2018

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Lassa fever in Guinea: II. Distribution and prevalence of Lassa virus infection in small mammals

21 January 2018

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Lassa serology in natural populations of rodents and horizontal transmission

21 January 2018

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Kinetics of protective antibodies are determined by the viral surface antigen

21 January 2018

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Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection

21 January 2018

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Serological and biological evidence that Lassa-complex arenaviruses are widely distributed in Africa

21 January 2018

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Density thresholds for Mopeia virus invasion and persistence in its host Mastomys natalensis.

21 January 2018

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Antibodies to Lassa and Lassa-like viruses in man and mammals in the Central African Republic

21 January 2018

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Protection of rhesus monkeys from Lassa virus by immunisation with closely related Arenavirus

21 January 2018

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Generation of reassortants between African arenaviruses

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: the case of lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Role of interferons in the control of Lassa virus replication in human dendritic cells and macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Early and strong immune responses are associated with control of viral replication and recovery in lassa virus-infected cynomolgus monkeys

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Low levels of interleukin-8 and interferon-inducible protein-10 in serum are associated with fatal infections in acute Lassa fever

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses

21 January 2018

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Human macrophages, but not dendritic cells, are activated and produce alpha/beta interferons in response to Mopeia virus infection

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Old and New World arenaviruses share a highly conserved epitope in the fusion domain of the glycoprotein 2, which is recognized by Lassa virus-specific human CD4+ T-cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Characterization of human CD4(+) T-cell clones recognizing conserved and variable epitopes of the Lassa virus nucleoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Endemic Lassa fever in Liberia. III. Characterization of Lassa virus isolates

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Early blood profiles of virus infection in a monkey model for Lassa fever.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Transcriptome analysis of human peripheral blood mononuclear cells exposed to Lassa virus and to the attenuated Mopeia/Lassa reassortant 29 (ML29), a vaccine candidate

21 January 2018

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Transcriptional profiling of the circulating immune response to lassa virus in an aerosol model of exposure

21 January 2018

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A recently isolated Lassa virus from Mali demonstrates atypical clinical disease manifestations and decreased virulence in cynomolgus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Delayed inflammatory and cell death responses are associated with reduced pathogenicity in Lujo virus-infected cynomolgus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

LCMV-mediated hepatitis in rhesus macaques: WE but not ARM strain activates hepatocytes and induces liver regeneration

21 January 2018

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Mucosal arenavirus infection of primates can protect them from lethal hemorrhagic fever.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Lassa fever. Effective therapy with ribavirin

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Lassa and Marburg viruses elicit distinct host transcriptional responses early after infection

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Immune responses and Lassa virus infection

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Inhibition of Innate Immune Responses Is Key to Pathogenesis by Arenaviruses

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Pathogenesis of arenavirus hemorrhagic fevers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Inactivated Lassa virus elicits a non protective immune response in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Shedding of soluble glycoprotein 1 detected during acute Lassa virus infection in human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Lassa virus activity in Guinea: distribution of human antiviral antibody defined using enzyme-linked immunosorbent assay with recombinant antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Effective vaccine for lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Advanced vaccine candidates for Lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

General Molecular Strategy for Development of Arenavirus Live-Attenuated Vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Vaccines for viral hemorrhagic fevers--progress and shortcomings

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Vaccination strategies against highly pathogenic arenaviruses: the next steps toward clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Argentine hemorrhagic fever vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Vaccinia recombinant expressing Lassa-virus internal nucleocapsid protein protects guineapigs against Lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Construction of a recombinant vaccinia virus expressing the Lassa virus glycoprotein gene and protection of guinea pigs from a lethal Lassa virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Development of a new vaccine for the prevention of Lassa fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Yellow fever 17D-vectored vaccines expressing Lassa virus GP1 and GP2 glycoproteins provide protection against fatal disease in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Protection of guinea pigs from Lassa fever by vaccinia virus recombinants expressing the nucleoprotein or the envelope glycoproteins of Lassa virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Protection of rhesus monkeys from fatal Lassa fever by vaccination with a recombinant vaccinia virus containing the Lassa virus glycoprotein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Absence of CTL responses to early viral antigens facilitates viral persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Cap binding and immune evasion revealed by Lassa nucleoprotein structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Recombination and gene coding assignments of bunyaviruses and arenaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Reassortant analysis of guinea pig virulence of pichinde virus variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Molecular characterization of a reassortant virus derived from Lassa and Mopeia viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Multifunctional nature of the arenavirus RING finger protein Z.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A ML29 reassortant virus protects guinea pigs against a distantly related Nigerian strain of Lassa virus and can provide sterilizing immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

The search for animal models for Lassa fever vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Vaccine Platforms to Control Arenaviral Hemorrhagic Fevers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

An attenuated Lassa vaccine in SIV-infected rhesus macaques does not persist or cause arenavirus disease but does elicit Lassa virus-specific immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Arenavirus-mediated liver pathology: acute lymphocytic choriomeningitis virus infection of rhesus macaques is characterized by high-level interleukin-6 expression and hepatocyte proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Genetic variation in vitro and in vivo of an attenuated Lassa vaccine candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

High fidelity of yellow fever virus RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Recombinant vesicular stomatitis viruses from DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Individual and bivalent vaccines based on alphavirus replicons protect guinea pigs against infection with Lassa and Ebola viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Preclinical and clinical development of YFV 17D-based chimeric vaccines against dengue, West Nile and Japanese encephalitis viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

Establishing efficacy of human products using animals: the US food and drug administration's "animal rule".

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1184575

10.1080/14760584.2016.1184575

21 January 2018

Identifiers

DOI

1 reference

6 September 2017

1 reference