(Q38824352)

6 September 2017

Oligomerization and GTP-binding Requirements of MxA for Viral Target Recognition and Antiviral Activity against Influenza A Virus (English)

1 reference

6 September 2017

Influenza A Virus

1 reference

Patricia E Nigg

1

1 reference

6 September 2017

Jovan Pavlovic

series ordinal

2

1 reference

6 September 2017

language of work or name

English

0 references

publication date

27 October 2015

1 reference

Journal of Biological Chemistry

6 September 2017

1 reference

6 September 2017

290

1 reference

6 September 2017

50

1 reference

6 September 2017

29893-29906

1 reference

describes a project that uses

6 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4706002/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.

9 September 2017

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9 September 2017

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Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke

9 September 2017

1 reference

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9 September 2017

1 reference

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Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

9 September 2017

1 reference

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Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein

9 September 2017

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9 September 2017

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Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly

9 September 2017

1 reference

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Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function

9 September 2017

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Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49

9 September 2017

1 reference

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The cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infection

9 September 2017

1 reference

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The viral nucleoprotein determines Mx sensitivity of influenza A viruses

9 September 2017

1 reference

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Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity

9 September 2017

1 reference

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Structural basis of oligomerization in the stalk region of dynamin-like MxA

9 September 2017

1 reference

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Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export

9 September 2017

1 reference

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The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus

9 September 2017

1 reference

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An intramolecular signaling element that modulates dynamin function in vitro and in vivo

9 September 2017

1 reference

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INTERFEROME: the database of interferon regulated genes

9 September 2017

1 reference

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Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase

9 September 2017

1 reference

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Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers

9 September 2017

1 reference

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Functional classification of interferon-stimulated genes identified using microarrays

9 September 2017

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

9 September 2017

1 reference

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Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesis

9 September 2017

1 reference

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

A functional GTP-binding motif is necessary for antiviral activity of Mx proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

cDNA structures and regulation of two interferon-induced human Mx proteins

9 September 2017

1 reference

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Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Mechanism of human MxA protein action: variants with changed antiviral properties

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

A monomeric GTPase-negative MxA mutant with antiviral activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Cell type-specific MxA-mediated inhibition of measles virus transcription in human brain cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Nondenaturing Polyacrylamide Gel Electrophoresis of Proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Overexpression of the influenza virus polymerase can titrate out inhibition by the murine Mx1 protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Dynamin self-assembly stimulates its GTPase activity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Vesicular stomatitis virus transcription inhibited by purified MxA protein

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virus

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for analysis of multiprotein complexes from cellular lysates

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Function of the mouse Mx1 protein is inhibited by overexpression of the PB2 protein of influenza virus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Oligomerization paths of the nucleoprotein of influenza A virus.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Domains mediating intramolecular folding and oligomerization of MxA GTPase.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4706002

Automated minimization of steric clashes in protein structures

22 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.681494

21 January 2018

Identifiers

DOI

10.1074/JBC.M115.681494

1 reference

release_4cn3vxa2e5g6hon4vbcwcdx2oq

6 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4cn3vxa2e5g6hon4vbcwcdx2oq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

6 September 2017

PubMed publication ID

26507657

1 reference