(Q38830205)

6 September 2017

title

A novel dual EGFR/HER2 inhibitor KU004 induces cell cycle arrest and apoptosis in HER2-overexpressing cancer cells (English)

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6 September 2017

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Chongchong Tian

1

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6 September 2017

Pingping Ding

2

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6 September 2017

Ziqiao Yuan

3

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6 September 2017

Han Li

4

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6 September 2017

Yanxia Zhao

5

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6 September 2017

Lan Sun

6

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6 September 2017

Qingming Guo

7

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6 September 2017

Zhenzhong Wang

8

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6 September 2017

Lixin Sun

9

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6 September 2017

Luyong Zhang

10

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6 September 2017

Zhenzhou Jiang

11

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6 September 2017

publication date

5 October 2015

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6 September 2017

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6 September 2017

volume

20

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6 September 2017

issue

12

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6 September 2017

page(s)

1599-1612

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https://scigraph.springernature.com/pub.10.1007/s10495-015-1164-7

6 September 2017

exact match

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cites work

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The role of HER2 in cancer therapy and targeted drug delivery

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Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer

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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

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21 January 2018

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HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target

21 January 2018

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HER-2/neu oncogene protein and prognosis in breast cancer

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The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine

21 January 2018

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Resistance to Trastuzumab in Breast Cancer.

21 January 2018

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Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer

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Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

21 January 2018

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KU004 induces G1 cell cycle arrest in human breast cancer SKBR-3 cells by modulating PI3K/Akt pathway

21 January 2018

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

21 January 2018

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Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells.

21 January 2018

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Exposure to mixtures of endosulfan and zineb induces apoptotic and necrotic cell death in SH-SY5Y neuroblastoma cells, in vitro

21 January 2018

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Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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RB kinases and RB-binding proteins: new points of view

21 January 2018

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Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

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Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines

21 January 2018

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Mutant p53: an oncogenic transcription factor

21 January 2018

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Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.

21 January 2018

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21 January 2018

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

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The Fas signaling pathway: more than a paradigm

21 January 2018

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21 January 2018

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Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

21 January 2018

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21 January 2018

The Cell Cycle: A Review

1 reference

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10.1007/S10495-015-1164-7

21 January 2018

Identifiers

DOI

1 reference

release_yqtqqgzsfzahjfp3gm4lmyjpwy

6 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yqtqqgzsfzahjfp3gm4lmyjpwy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference