(Q38838739)

14 June 2018

title

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates (English)

1 reference

14 June 2018

7

David Rabuka

1 reference

14 June 2018

author name string

Thomas Botzanowski

1

1 reference

14 June 2018

Stéphane Erb

2

1 reference

14 June 2018

Oscar Hernandez-Alba

3

1 reference

14 June 2018

Anthony Ehkirch

4

1 reference

14 June 2018

Olivier Colas

5

1 reference

14 June 2018

Elsa Wagner-Rousset

6

1 reference

14 June 2018

Alain Beck

8

1 reference

14 June 2018

Penelope M Drake

9

1 reference

14 June 2018

Sarah Cianférani

10

1 reference

14 June 2018

publication date

13 April 2017

1 reference

14 June 2018

published in

Monoclonal Antibodies

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14 June 2018

volume

9

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14 June 2018

issue

5

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14 June 2018

page(s)

801-811

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14 June 2018

Strategies and challenges for the next generation of antibody-drug conjugates

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

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17 June 2018

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Antibodies to watch in 2017

17 June 2018

1 reference

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Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates

17 June 2018

1 reference

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Mechanisms of Resistance to Antibody-Drug Conjugates

17 June 2018

1 reference

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Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice

17 June 2018

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RN927C, a Site-Specific Trop-2 Antibody-Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models

17 June 2018

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Efficient Payload Delivery by a Bispecific Antibody-Drug Conjugate Targeting HER2 and CD63.

17 June 2018

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Insights from native mass spectrometry and ion mobility-mass spectrometry for antibody and antibody-based product characterization.

17 June 2018

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Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II).

17 June 2018

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Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

17 June 2018

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CIUSuite: A Quantitative Analysis Package for Collision Induced Unfolding Measurements of Gas-Phase Protein Ions.

17 June 2018

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17 June 2018

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Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.

17 June 2018

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Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate

17 June 2018

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Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation

17 June 2018

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CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.

17 June 2018

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Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates

17 June 2018

1 reference

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Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes

17 June 2018

1 reference

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Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Transglutaminase-based chemo-enzymatic conjugation approach yields homogeneous antibody-drug conjugates.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Site-specific antibody drug conjugates for cancer therapy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Synthesis of site-specific antibody-drug conjugates using unnatural amino acids

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Site-specific chemical protein conjugation using genetically encoded aldehyde tags

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Strategies and challenges for the next generation of therapeutic antibodies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Next-Generation Antibody-Drug Conjugates (ADCs) for Cancer Therapy.

17 June 2018

1 reference

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Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Antibody-drug conjugates: present and future.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Mass spectrometric characterization of transglutaminase based site-specific antibody-drug conjugates.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Considerations for the nonclinical safety evaluation of antibody drug conjugates for oncology

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Fourth World Antibody-Drug Conjugate Summit: February 29-March 1, 2012, Frankfurt, Germany

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524152

Dynamics of Intact Immunoglobulin G Explored by Drift-Tube Ion-Mobility Mass Spectrometry and Molecular Modeling

22 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2017.1316914

Ion mobility–mass spectrometry analysis of large protein complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28406343

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28406343

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/19420862.2017.1316914

1 reference

14 June 2018

PMCID

5524152

1 reference

14 June 2018

PubMed ID

28406343

1 reference

14 June 2018