(Q38841449)

6 September 2017

Lack of Evidence for PKM2 Protein Kinase Activity (English)

1 reference

6 September 2017

Aaron M Hosios

1

1 reference

6 September 2017

Brian P Fiske

series ordinal

2

1 reference

6 September 2017

Dan Y Gui

series ordinal

3

1 reference

6 September 2017

Matthew G Vander Heiden

series ordinal

4

1 reference

6 September 2017

19 August 2015

1 reference

6 September 2017

1 reference

6 September 2017

59

1 reference

6 September 2017

5

1 reference

6 September 2017

850-857

1 reference

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

PKM2 regulates chromosome segregation and mitosis progression of tumor cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Functional lysine modification by an intrinsically reactive primary glycolytic metabolite

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

The quantitative proteome of a human cell line.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Pyruvate kinase M2 is a phosphotyrosine-binding protein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Metabolic characteristics of different malignant cancer cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Cell cycle-dependent regulation of cellular ATP concentration, and depolymerization of the interphase microtubular network induced by elevated cellular ATP concentration in whole fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Nonenzymatic phosphorylation of tyrosine and serine by ATP is catalyzed by manganese but not magnesium

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

Please keep me 2uned to PKM2.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4548833

A Kinetic Study of Nucleotide Interactions with Pyruvate Kinase*

22 August 2018

1 reference

12 December 2020

Effect of vanadate on the formation and stability of the phosphoenzyme forms of 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase and of phosphoglucomutase

1 reference

12 December 2020

An enzymatic method for [32P]phosphoenolpyruvate synthesis

1 reference

12 December 2020

Extraction, purification and analysis of histones

1 reference

12 December 2020

10.1016/J.MOLCEL.2015.07.013

Identifiers

DOI

1 reference

6 September 2017

1 reference

6 September 2017

PubMed publication ID

26300261

1 reference