(Q38904799)

7 September 2017

title

Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma (English)

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7 September 2017

Y Gui

1

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7 September 2017

M Yeganeh

2

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7 September 2017

Y-C Donates

3

1 reference

7 September 2017

W-S Tobelaim

4

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7 September 2017

W Chababi

5

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7 September 2017

M Mayhue

6

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7 September 2017

A Yoshimura

7

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7 September 2017

S Ramanathan

8

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7 September 2017

C Saucier

9

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7 September 2017

S Ilangumaran

10

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7 September 2017

language of work or name

English

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publication date

2 March 2015

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7 September 2017

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7 September 2017

volume

34

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7 September 2017

issue

46

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7 September 2017

page(s)

5718-5728

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https://scigraph.springernature.com/pub.10.1038/onc.2015.20

7 September 2017

exact match

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cites work

SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

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SOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes

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Drug development of MET inhibitors: targeting oncogene addiction and expedience

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MET signalling: principles and functions in development, organ regeneration and cancer

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Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway.

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Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation.

21 January 2018

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Dorsal ruffle microdomains potentiate Met receptor tyrosine kinase signaling and down-regulation

21 January 2018

1 reference

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Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.20

Down-regulation of MET, the receptor for hepatocyte growth factor.

21 January 2018

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Are SOCS suppressors, regulators, and degraders?

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The Role of Elongin BC-Containing Ubiquitin Ligases

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Demonstration of cooperative contribution of MET- and EGFR-mediated STAT3 phosphorylation to liver regeneration by exogenous suppressor of cytokine signalings.

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Regulation of the immune system by SOCS family adaptor proteins

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Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

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Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

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ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells

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c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

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Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors

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MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene

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Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

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Identification of miR-30d as a novel prognostic maker of prostate cancer

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

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Spatial regulation of receptor tyrosine kinases in development and cancer

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Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors

21 January 2018

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Receptor tyrosine kinase coactivation networks in cancer

21 January 2018

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Targeting MET in cancer: rationale and progress

21 January 2018

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From Tpr-Met to Met, tumorigenesis and tubes.

21 January 2018

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Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

21 January 2018

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The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

21 January 2018

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21 January 2018

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Targeting the HGF/c-MET pathway in hepatocellular carcinoma

21 January 2018

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Aberrant DNA methylation as a cancer-inducing mechanism

21 January 2018

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Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms

21 January 2018

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Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.20

A positive regulatory role for suppressor of cytokine signaling 1 in IFN-gamma-induced MHC class II expression in fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2015.20

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.20

Suppressors of cytokine signalling (SOCS) in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.20

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25728680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Receptor chimeras indicate that the met tyrosine kinase mediates the motility and morphogenic responses of hepatocyte growth/scatter factor.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25728680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SOCS, inflammation, and cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25728680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2015.20

1 reference

Dimensions Publication ID

7 September 2017

1048889484

0 references

1 reference