(Q38904869)

7 September 2017

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title

Role of tumor-associated macrophages in human malignancies: friend or foe? (English)

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7 September 2017

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Motohiro Takeya

1

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7 September 2017

Yoshihiro Komohara

series ordinal

2

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7 September 2017

publication date

21 July 2016

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7 September 2017

published in

Pathology International

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7 September 2017

volume

66

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7 September 2017

issue

9

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7 September 2017

page(s)

491-505

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

7 September 2017

cites work

1 reference

Distinct role of macrophages in different tumor microenvironments

21 January 2018

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Clinical significance of macrophage heterogeneity in human malignant tumors

21 January 2018

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Tumour-educated macrophages promote tumour progression and metastasis

21 January 2018

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

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Fate mapping analysis reveals that adult microglia derive from primitive macrophages

21 January 2018

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The origin and kinetics of mononuclear phagocytes

21 January 2018

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Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas

21 January 2018

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M-1/M-2 macrophages and the Th1/Th2 paradigm

21 January 2018

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Macrophage activation and polarization: nomenclature and experimental guidelines

21 January 2018

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The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

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Exploring the full spectrum of macrophage activation

21 January 2018

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Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms

21 January 2018

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Alternative activation of macrophages: an immunologic functional perspective

21 January 2018

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The M1 and M2 paradigm of macrophage activation: time for reassessment

21 January 2018

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Microenvironmental regulation of tumor progression and metastasis

21 January 2018

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The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

21 January 2018

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Tumor-associated macrophages: from mechanisms to therapy

21 January 2018

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Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma.

21 January 2018

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Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies

21 January 2018

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Revisiting STAT3 signalling in cancer: new and unexpected biological functions

21 January 2018

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Importance of direct macrophage-tumor cell interaction on progression of human glioma.

21 January 2018

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STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

21 January 2018

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CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

21 January 2018

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S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

21 January 2018

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High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis

21 January 2018

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Human breast cancer cells educate macrophages toward the M2 activation status

21 January 2018

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The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

21 January 2018

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In human invasive breast ductal carcinoma, tumor stromal macrophages and tumor nest macrophages have distinct relationships with clinicopathological parameters and tumor angiogenesis.

21 January 2018

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The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer

21 January 2018

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Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival.

21 January 2018

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Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

21 January 2018

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Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma.

21 January 2018

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Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: possible contribution of Cd204-positive macrophages to the tumor-promoting microenvironment.

21 January 2018

1 reference

Circulating CD14+CD204+ cells predict postoperative recurrence in non-small-cell lung cancer patients

21 January 2018

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Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung

21 January 2018

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High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection.

21 January 2018

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The clinical significance of the CD163+ and CD68+ macrophages in patients with hepatocellular carcinoma.

21 January 2018

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Tumor-infiltrating macrophages can predict favorable prognosis in hepatocellular carcinoma after resection.

21 January 2018

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CD68(+)HLA-DR(+) M1-like macrophages promote motility of HCC cells via NF-κB/FAK pathway

21 January 2018

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Macrophages: Good guys in colorectal cancer

21 January 2018

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The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer

21 January 2018

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Intratumoral macrophage counts correlate with tumor progression in colorectal cancer

21 January 2018

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Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time.

21 January 2018

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21 January 2018

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The role of macrophages polarization in predicting prognosis of radically resected gastric cancer patients

21 January 2018

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The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression

21 January 2018

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The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

21 January 2018

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Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma

21 January 2018

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Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients.

21 January 2018

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Immunohistochemical analysis of inflammatory cells in benign and precancerous lesions and carcinoma of the prostate

21 January 2018

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Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

21 January 2018

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Density of tumor-associated macrophages correlates with lymph node metastasis in papillary thyroid carcinoma

21 January 2018

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Infiltration of a mixture of immune cells may be related to good prognosis in patients with differentiated thyroid carcinoma.

21 January 2018

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Circulating CD14(+) CD16(+) monocyte levels predict tissue invasive character of cholangiocarcinoma.

21 January 2018

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Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma.

21 January 2018

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Angiogenesis in renal cell carcinoma: the role of tumor-associated macrophages

21 January 2018

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Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma

21 January 2018

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Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma.

21 January 2018

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Prognostic value of diametrically polarized tumor-associated macrophages in renal cell carcinoma

21 January 2018

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The Coordinated Actions of TIM-3 on Cancer and Myeloid Cells in the Regulation of Tumorigenicity and Clinical Prognosis in Clear Cell Renal Cell Carcinomas.

21 January 2018

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Overexpression of cyclooxygenase-2 in urothelial carcinoma in conjunction with tumor-associated-macrophage infiltration, hypoxia-inducible factor-1alpha expression, and tumor angiogenesis

21 January 2018

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High CD204+ tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder

21 January 2018

1 reference

Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation

21 January 2018

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Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors.

21 January 2018

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A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

21 January 2018

1 reference

Immunosuppressive tumor microenvironment in cervical cancer patients

21 January 2018

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Polarisation of Tumor-Associated Macrophages toward M2 Phenotype Correlates with Poor Response to Chemoradiation and Reduced Survival in Patients with Locally Advanced Cervical Cancer

21 January 2018

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Macrophage polarisation: an immunohistochemical approach for identifying M1 and M2 macrophages.

21 January 2018

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Tumor-associated macrophages and CD3-zeta expression of tumor-infiltrating lymphocytes in human esophageal squamous-cell carcinoma

21 January 2018

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Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma.

21 January 2018

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Macrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro

21 January 2018

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Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.

21 January 2018

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Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas.

21 January 2018

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Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response

21 January 2018

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Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants

21 January 2018

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Turnover of resident microglia in the normal adult mouse brain

21 January 2018

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Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme

21 January 2018

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Expression and localization of VEGF-C and VEGFR-3 in glioblastomas and haemangioblastomas.

21 January 2018

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Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling

21 January 2018

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Distribution and characterization of microglia/macrophages in human brain tumors.

21 January 2018

1 reference

Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A.

21 January 2018

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Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma.

21 January 2018

1 reference

Detection of M2-macrophages in uveal melanoma and relation with survival.

21 January 2018

1 reference

Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

21 January 2018

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Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial

21 January 2018

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CD163 immunohistochemistry is superior to CD68 in predicting outcome in classical Hodgkin lymphoma.

21 January 2018

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CD163 expression was associated with angiogenesis and shortened survival in patients with uniformly treated classical Hodgkin lymphoma

21 January 2018

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Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma

21 January 2018

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Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival

21 January 2018

1 reference

Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

21 January 2018

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Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).

21 January 2018

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High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial.

21 January 2018

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A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone.

21 January 2018

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M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro.

21 January 2018

1 reference

The Prognostic Impact of CD163-Positive Macrophages in Follicular Lymphoma: A Study from the BC Cancer Agency and the Lymphoma Study Association.

21 January 2018

1 reference

Clinical significance of CD163⁺ tumor-associated macrophages in patients with adult T-cell leukemia/lymphoma

21 January 2018

1 reference

Role of CD204-positive tumor-associated macrophages in adult T-cell leukemia/lymphoma

21 January 2018

1 reference

High numbers of CD68+ tumor-associated macrophages correlate with poor prognosis in extranodal NK/T-cell lymphoma, nasal type

21 January 2018

1 reference

Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma

21 January 2018

1 reference

Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204).

21 January 2018

1 reference

Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy

21 January 2018

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The interaction of anticancer therapies with tumor-associated macrophages

21 January 2018

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Transcriptional regulation of macrophage polarization: enabling diversity with identity

21 January 2018

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Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/PIN.12440

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7 September 2017

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